1. Sulfanilamide should be sterilized before it is placed in clean wounds.
2. Joints and other tissues which we have investigated tolerate the drug very well.
3. The powder slightly inhibits the primary healing of the wound, but not to such a degree as to contra-indicate its use in clean operative wounds.
4. It may be used repeatedly in open infected wounds and does not seriously interfere with the healing of such wounds.
5. We not only advocat. the local implantation of sulfanilamide in contaminated wounds, but we also advocate its use in clinically clean operative wounds where infection is especially to be feared or would be particularly undesirable.