Herewith is presented the case of a syphilitic girl, aged fourteen, whose spine was first punctured on June 20, 1936, without any untoward effects. On September 4, 1937, she was subjected to several unsuccessful spinal taps. These were followed by immediate clinical manifestations of Some local disturbance at the site of these taps. Lumbar hyperextension and severe pain were replaced within five weeks by lumbar flexion and prominence of the spinous processes of the second and fourth lumbar vertebrae. Roentgenograms on September 8, 1937, were read as negative for bone pathology, but, as time went on, subsequent plates from October 1937, until the final date of observation in April 1939, gave evidence of narrowing of the affected joint spaces, compensatory widening of the adjacent joint spaces, and the development of the characteristic interarticular, intra-osseous Schmorl's nodules which are generally regarded as pathognomonic of intervertebral-disc disturbance. The entire succession of events in this case is so direct and clear that it is difficult to escape the conclusion that the described end results followed the misadventurous spinal puncture.