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OPEN VERSUS CLOSED TREATMENT OF ACUTE OSTEOMYELITIS A Clinical Report on the Use of Antitoxin and the Sulfonamide Drugs with and without Early Drainage
Lenox D. Baker; Howard J. Schaubel; Harold H. Kuhn
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Department of Surgery, Division of Orthopaedics, Duke University School of Medicine, Durham
1944 by The American Orthopaedic Association, Inc.
The Journal of Bone & Joint Surgery.  1944; 26:345-349 
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Abstract

1. A well-planned, useful, supportive routine is necessary for osteomyeitic patients.

2. Staphylococcus toxins can be neutralized in vivo by antitoxin prepared from Burky's Ha strain of hemolytic staphylococcus aureus.

3. The mortality rate in hemolytic staphylococcus aureus osteomyelitis can be lowered by the use of sulfathiazole, sulfadiazine, or both.

4. The morbidity of the disease can be reduced if surgical drainage is not used.

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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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