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Clinical Evaluation of the Merthiolate Bone Bank. A Preliminary Report
Fred C. Reynolds; David R. Oliver
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St. Louis, Missouri
1949 by The American Orthopaedic Association, Inc.
The Journal of Bone & Joint Surgery.  1949; 31:793-814 
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Abstract

1. The process of fixation and replacement of both autogenous and known dead homogenous bone grafts is accomplished in an identical manner, experimentally and clinically.

2. The merthiolate bone bank offers a simple, inexpensive, and aseptic method of preserving homogeneous bone.

3. Merthiolate-preserved bone is well tolerated in the tissues, and early results obtained with grafts from the merthiolate bone bank compare favorably with autogenous grafts under similar circumstances.

See image in the PDF file

4. No sensitivity to merthiolate has been encountered in any case.

5. Experimentally and clinically, the early phases of healing are somewhat slower with homogenous grafts than with autogenous grafts. Therefore, it is important that immobilization be continued over a longer period of time.

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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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