JBJS | NOTE ON THE USE OF NITROGEN MUSTARD IN RHEUMATOID ARTHRITIS With Consideration of the Similarity of Its Effect to That of Cortisone and ACTH

The Journal of Bone & Joint Surgery, Volume 33, Issue 1

Journal Contents | January 01, 1951

NOTE ON THE USE OF NITROGEN MUSTARD IN RHEUMATOID ARTHRITIS With Consideration of the Similarity of Its Effect to That of Cortisone and ACTH

NED M. SHUTKIN

View Disclosures and Other Information

Orthopaedic Division, Department of Surgery, Duke University School of Medicine, Durham

1950 by The American Orthopaedic Association, Inc.

The Journal of Bone & Joint Surgery. 1951; 33:265-267

5 Recommendations (Recommend) | 3 Comments | Saved by 3 Users Save Case

Article

text A A A

Abstract

1. Six patients with active rheumatoid arthritis showed prompt, but transient, improvement after the administration of nitrogen mustard.

2. Nitrogen mustard produces depletion of the cholesterol esters and ascorbic acid of the adrenal cortex in the experimental animal.

3. ACTH produces depletion of the cholesterol esters and ascorbic acid of the adrenal cortex.

4. Further investigation to determine the efficacy of nitrogen mustard in the treatment of rheumatoid arthritis is indicated.

Figures in this Article

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Topics

Accreditation Statement

These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.

CME Activities Associated with This Article

Submit a Comment

Please read the other comments before you post yours. Contributors must reveal any conflict of interest.
Comments are moderated and will appear on the site at the discretion of JBJS editorial staff.

* = Required Field

Comment Author(s) * (if multiple authors, separate names by comma)

Example: John Doe

Affiliation & Institution*

Comment Title*

Comment*

Cancel

Print
PDF
Email

Recipient(s) will receive an email with a link (good for 5 Days) to 'NOTE ON THE USE OF NITROGEN MUSTARD IN RHEUMATOID ARTHRITIS With Consideration of the Similarity of Its Effect to That of Cortisone and ACTH' and do not need to have The Journal of Bone & Joint Surgery account to access the content.
Your Name:*
Example: John Doe

Email Address:* CC Me:
Enter your valid email address. Example: jdoe@example.com

Recipient's Email Address:*

Separate multiple email address with semi-colons (up to 5).

Subject:* 's The Journal of Bone & Joint Surgery: 'NOTE ON THE USE OF NITROGEN MUSTARD IN RHEUMATOID ARTHRITIS With Consideration of the Similarity of Its Effect to That of Cortisone and ACTH'
Subject for your email.

Message:

(Optional, message will truncate at 1000 characters)

Processing your request... Please Wait...

Copyright © in the material you requested is held by The Journal of Bone & Joint Surgery, Inc. (unless otherwise noted). This email ability is provided as a courtesy, and by using it you agree that that you are requesting the material solely for personal, non-commercial use, and that it is subject to Journal of Bone & Joint Surgery, Inc.'s Terms of Use. The information provided in order to email this topic will not be used to send unsolicited email, nor will it be furnished to third parties. Please refer to The Journal of Bone & Joint Surgery Inc.'s Privacy Policy for further information.

Copyright © The Journal of Bone & Joint Surgery Inc. All rights reserved.
Share
Get Citation

NED M. SHUTKIN; NOTE ON THE USE OF NITROGEN MUSTARD IN RHEUMATOID ARTHRITIS With Consideration of the Similarity of Its Effect to That of Cortisone and ACTH. The Journal of Bone & Joint Surgery. 1951 Jan;33(1):265-267.

Download citation file:

RIS (Zotero)

EndNote

BibTex

Medlars

ProCite

RefWorks

Reference Manager

Copyright © The Journal of Bone and Joint Surgery, Inc.
Rights & Permissions
Sign Up for Alerts on this
Article

Processing your request... Please Wait.
Submit a Comment