Pain over the pisiform bone and weakness of grip are the characteristic symptoms of the clinical syndrome of calcified pisiform bursitis. The calcific deposit is adjacent to the pisiform bone and is located either within the tendon of the flexor carpi ulnaris or within the bursa of the flexor carpi ulnaris muscle. The diagnosis is frequently missed because the calcification is usually demonstrated only on oblique roentgenograms of the wrist. Surgical excision of the calcification should be resorted to only if more conservative treatment fails to give relief. The majority of patients with this condition are promptly cured by local infiltration of the calcified area.