In this experiment, 141 split-rib grafts implanted into mature dogs showed the following:
1. All grafts were successfully transplanted in that they were incorporated into the host osteogenic bed.
2. Histological examination revealed osteogenic cells and osteocytes to survive only in fresh autogenous bone grafts. This osteogenetic activity was found to take part in the incorporation of the graft into the host tissue.
3. Fresh autogenous bone grafts were more readily tolerated by the host tissue than the preserved bone grafts or fresh homogenous grafts.