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Ultrasonic Energy and Surgically Produced Defects in Bone
NICHOLAS I. ARDANJR.; JOSEPH M. JANES; J. F. HERRICK
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Section of Orthopaedic Surgery and the Section of Biophysics and Biophysical Research, Mayo Clinic and Mayo Foundation, Rochester
1957 by The Journal of Bone and Joint Surgery, Incorporated
The Journal of Bone & Joint Surgery.  1957; 39:394-402 
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Abstract

A study was made of the effect of ultrasonic energy on the healing of defects created surgically in the femora of sixty-seven dogs. The ultrasonic energy was applied to anaesthetized dogs with a power ranging from five to twenty-five watts in various groups of animals.

Stimulation of the healing of these defects its bone was not seen. Instead, a delay in healing associated with medullary fibrosis and necrosis of bone was noted. This agrees in part at least with work reported by others. In view of recently reported studies claiming stimulation of the healing of fractures following use of a different technique of ultrasonic application and smaller doses, the need for further investigation along these lines is obvious.

It is probable that more frequent and less concentrated exposures, with use of a technique and dosage comparable to those used clinically, applied to non-anaesthetized animals would provide the answer to this question. Now that the effects of more intensive amounts of energy have been studied, this would appear to be the next step.

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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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