JBJS | Immunological Factors in Homogenous-Bone Transplantation III. The Inability of Homogenous Rabbit Bone to Induce Circulating Antibodies in Rabbits

The Journal of Bone & Joint Surgery, Volume 41, Issue 8

Journal Contents | December 01, 1959

Immunological Factors in Homogenous-Bone Transplantation III. The Inability of Homogenous Rabbit Bone to Induce Circulating Antibodies in Rabbits

Paul H. CurtissJR.; A. E. Powell; Charles H. Herndon

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Department of Orthopaedic Surgery and the Department of Surgery of the Western Reserve University School of Medicine and the University Hospitals of Cleveland, Cleveland

1959 by The Journal of Bone and Joint Surgery, Incorporated

The Journal of Bone & Joint Surgery. 1959; 41:1482-1488

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Abstract

Groups of rabbits were injected with soluble and insoluble portions of rabbit bone. No circulating antibody could be detected by binding of radioiodinated gamma globulin, erythrocyte hemagglutination, or agar-gel diffusion.

Insignificant differences in properdin titer were observed in rabbit sera following experimentally produced fractures, autografts, and homografts.

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These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.

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Paul H. CurtissJR., A. E. Powell, Charles H. Herndon; Immunological Factors in Homogenous-Bone Transplantation III. The Inability of Homogenous Rabbit Bone to Induce Circulating Antibodies in Rabbits. The Journal of Bone & Joint Surgery. 1959 Dec;41(8):1482-1488.

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