In a previous report2 of two sisters with bone tumors, we suggested that one tumor (C.R.M.'s) was a typical Ewing tumor and that the other (M.J.E.'s) a most unusual Ewing tumor. We present here the concluding clinical course and the autopsy findings in the case of M.J.E. The metastatic lesion in the right side of the chest had responded to irradiation. At autopsy, there was a good deal of tumor in the left side of the chest and none elsewhere. Nothing was found to suggest lymphoma, neuroblastoma, or small-cell carcinoma. We are unable to suggest a reasonable alternative to the hypothesis that this was an atypical Ewing tumor.