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Paget's Disease of the Skull and Facial Bones
Bernard J. Drury
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Sansum Medical Clinic, Santa Barbara
1962 by The Journal of Bone and Joint Surgery, Incorporated
The Journal of Bone & Joint Surgery.  1962; 44:174-179 
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Abstract

Hyperostosis of the facial bones caused by Paget's disease is rare and usually occurs after fifty years of age. When hyperostosis of this type is termed leontiasis ossea there is confusion as to the etiology. It is my belief that rather than using the term leontiasis ossea, a definite disease should be identified with the facial hyperostosis. The only reliable method of determining the etiology is biopsy and microscopic identification.

Paget's disease of the facial bones has usually been treated symptomatically for the relief of pressure on vital structures. Since Paget's disease in other sites has responded to treatment, especially with combinations of estrogen and androgen and with corticosteroids, I believe hormone therapy of this type should at least be tried in an effort to relieve symptoms and to stop the seemingly uncontrollable bone growth.

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    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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