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A Comparative Study of the Healing Process Following Different Types of Bone Transplantation
KINGSBURY G. HEIPLE; SAMUEL W. CHASE; CHARLES H. HERNDON
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From the Division of Orthopaedic Surgery and the Department of Anatomy, Western Reserve University School of Medicine and University Hospitals, Cleveland
1963 by The Journal of Bone and Joint Surgery, Incorporated
The Journal of Bone & Joint Surgery.  1963; 45:1593-1616 
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Abstract

A controlled comparative study was made of the osteogenic properties of various types of bone grafts in dogs. A rating scale was applied to the histological criteria used for the evaluation of the grafts, and a tabular and statistical evaluation of the results was carried out. Fresh autogenous bone was clearly superior; freezedried homogenous bone was the next highest in rating. The rest of the grafts tested rated in the following order: frozen homogenous, decalcified homogenous, frozen irradiated homogenous, freeze-dried irradiated homogenous, fresh homogenous, deproteinized heterogenous, and deproteinized homogenous. An indication of the approximate level of significance of this ranking was given. The deficiencies in the data related to the great variability in the response of the animals and the small numbers of animals at each test interval are discussed.

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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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