JBJS | The Roentgenographic Development of Radiostrontium (Sr90)- Induced Osteogenic Sarcoma in the Rat

The Journal of Bone & Joint Surgery, Volume 47, Issue 2

Journal Contents | March 01, 1965

The Roentgenographic Development of Radiostrontium (Sr90)- Induced Osteogenic Sarcoma in the Rat

THOMAS W. POZNANSKI; SAM FRANKEL; MARVIN DAVIS

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216 South Kingshighway, St. Louis, Missouri 63110

1965 by The Journal of Bone and Joint Surgery, Incorporated

The Journal of Bone & Joint Surgery. 1965; 47:349-374

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Abstract

1. The development of the roentgenographic changes associated with radiostrontium (Sr⁹⁰)-induced osteogenic sarcomata in the young adult rat is described. Macroscopic and histological features of these neoplasms are also discussed.

2. Intraperitoneal administration of 0.75 microcurie of Sr⁹⁰ per gram of body weight causes an incidence of osteogenic sarcoma of 65 per cent.

3. The greatest percentage of neoplasms (58.8 per cent) occurred in the spine, followed by 28 per cent in the long bones.

4. The roentgenographic characteristics of Sr⁹⁰-induced osteogenic sarcomata in the rat and mouse are compared.

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THOMAS W. POZNANSKI, SAM FRANKEL, MARVIN DAVIS; The Roentgenographic Development of Radiostrontium (Sr90)- Induced Osteogenic Sarcoma in the Rat. The Journal of Bone & Joint Surgery. 1965 Mar;47(2):349-374.

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