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Malignant Hemangioendothelioma of Bone REPORT OF TWO CASES AND REVIEW OF THE LITERATURE
WARNER D. BUNDENSJR.; CARL T. BRIGHTON
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Temple University School of Medicine, Philadelphia, Pennsylvania Orthopaedic Service, United States Naval Hospital, Great Lakes, Illinois
1965 by The Journal of Bone and Joint Surgery, Incorporated
The Journal of Bone & Joint Surgery.  1965; 47:762-772 
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Abstract

1. Two cases of malignant hemangioendothelioma of bone are presented, and the world's literature is reviewed. In all, there are thirty-four adequately documented cases of this rare primary bone tumor.

2. The clinical and roentgenographic features are non-specific.

3. The histological characteristic of this lesion is an overproduction of atypical endothelial cells that frequently form anastomosing vascular clefts.

4. Prognosis and treatment are discussed.

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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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