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Measurement of Ligamentous Strength in Rat Knees
CHARLES M. TIPTON; RICHARD J. SCHILD; ADRIAN E. FLATT
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From the Exercise Physiology Laboratory, Department of Physiology and Biophysics, the Department of Physical Education, and the Department of Orthopaedic Surgery, The University of Iowa, Iowa City
1967 by The Journal of Bone and Joint Surgery, Incorporated
The Journal of Bone & Joint Surgery.  1967; 49:63-72 
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Abstract

Data have been presented relative to the strength and force-elongation relationships of rat ligaments. The findings indicated that the testing methods employed are sufficiently reliable for experimental purposes. Results showed that body weight, sex, and age of the animals are important parameters when evaluating separation force results. Absence of adrenal or thyroid glands had no significant influence on the strength of the medial collateral ligament. It was concluded that the strength of the medial collateral ligament was dependent upon its osseous attachment.

Force-elongation data suggested that ligamentous strength and elongation are independent properties. Ligaments from adrenalectomized and thyroidectomized rats exhibited significantly more elongation than ligaments from normal rats. The responsible mechanisms are unknown and are the focus for current studies.

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    Accreditation Statement
    These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.
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