A case of extracutaneous sporotrichosis causing arthritis of a metacarpophalangeal joint of the hand, and tenosynovitis of the extensor carpi ulnaris has been reported. Iodide therapy, as is frequently the case, was not successful and the toxicity of amphotericin B precluded the administration of a curative dose. However, the combination of synovectomy and amphotericin-B therapy was effective, with no evidence of residual infection three years after the completion of treatment.