One hundred and fifty-three patients, forty-eight to ninety-seven years
old, were included in a double-blind placebo-controlled investigation of
the usefulness of hydroxychloroquine sulphate for the prevention of deep
venous thrombosis in patients with fractures of the hip, pelvis, or
thoracolumbar spine. The results indicated that this drug can reduce the
number of thrombeombolic complications significantly (p less than 0.005), a
finding that corresponds to the results obtained with other drugs such as
coumarin derivatives or dextran 70.