In rabbits, joint resurfacing with autologous osteoarticular condylar
grafts composed of the articular cartilage and subchondral bone (two to
eight millimeters thick) from the lateral femoral condyles was
investigated. By means of morphological, histochemical, autoradiographic,
and biochemical studies, the grafts were compared with sham and normal
controls. When adequately fixed, the grafts remained viable and
functionally and structurally intact during the twelve months of the
experiment. The subchondral bone underwent rapid replacement in less than
six weeks without loss of its supportive function. Resurfacing of a joint
using an osteochondral graft is feasible in rabbits.