We performed seven total hip replacements in six patients with the adult
form of Gaucher's disease. Excessive perioperative hemorrhage was a common
complication, and three patients have required revision of loosened
components. Two of these were young patients with a more severe form of the
disease. Total hip replacement is feasible and likely to be successful in
the older patient with Gaucher's disease and osteonecrosis or failed prior
hip surgery.