We examined samples of tissue and components that had been removed
during twenty revisions of total hip arthroplasties in which a
titanium-alloy femoral component had been used. Minute amounts of metallic
debris were detected in the tissues from two patients. The amounts of
polyethylene and methylmethacrylate debris and the histological reactions
in the tissues corresponded closely with those reported in earlier studies
of total hip prostheses made of stainless steel or cobalt-chromium
alloy.