Methods of meta-analysis, a technique for the combination of data from
multiple sources, were applied to analyze 106 reports of the treatment of
displaced fractures of the femoral neck. Two years or less after primary
internal fixation of a displaced fracture of the femoral neck, a non-union
had developed in 33 per cent of the patients and avascular necrosis, in 16
per cent. The rate of performance of a second operation within two years
ranged from 20 to 36 per cent after internal fixation and from 6 to 18 per
cent after hemiarthroplasty (relative risk, 2.6; 95 per cent confidence
interval, 1.4 to 4.6). Conversion to an arthroplasty was the most common
reoperation after internal fixation and accounted for about two-thirds of
these procedures. The remaining one-third of the reoperations were for
removal of the implant or revision of the internal fixation. For the
patients who had had a hemiarthroplasty, the most common reoperations were
conversion to a total hip replacement, removal or revision of the
prosthesis, and debridement of the wound. Although we observed an increase
in the rate of mortality at thirty days after primary hemiarthroplasty
compared with that after primary internal fixation, the difference was not
significant (p = 0.22) and did not persist beyond three months. The
absolute difference in perioperative mortality between the two groups was
small. An anterior operative approach for arthroplasty consistently was
associated with a lower rate of mortality at two months than was a
posterior approach. Some reports showed promising results after total hip
replacement for displaced fractures of the femoral neck; however,
randomized clinical trials are still needed to establish the value of this
treatment.