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Absence of Avascular Necrosis of the Humeral Head after Post-Traumatic Rupture of the Anterior and Posterior Humeral Circumflex Arteries. A Case Report*
CHRISTIAN GERBER, M.D.†; SIMON M. LAMBERT, M.D.‡; HENRI M. HOOGEWOUD, M.D.‡, FRIBOURG, SWITZERLAND
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Investigation performed at the Departments of Orthopaedics and Radiology, Hôpital Cantonal, Fribourg
The Journal of Bone & Joint Surgery.  1996; 78:1256-9 
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The vascularity of the proximal aspect of the humerus has recently been studied in detail2,6. The anterior humeral circumflex artery appears to be the main blood supply to the humeral head, while the posterior humeral circumflex artery has the most sizable anastomoses. The role of the intraosseous blood supply has been difficult to assess quantitatively, given the fact that no method has been developed to study the blood supply to the humeral head after complete obstruction of the major vessels. We recently examined a patient who had rupture of both circumflex arteries, as documented with angiography and operative observation, in association with a traumatic anterior dislocation of the shoulder. There was no evidence of avascular necrosis of the humeral head on radiographs or magnetic resonance images made eighteen months after the injury.

*No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.

†Department of Orthopaedics, University of Zurich, Balgrist, 8008 Zurich, Switerland.

‡Departments of Orthopaedics (S. M. L.) and Radiology (H. M. H.), Hôpital Cantonal, 1708 Fribourg, Switzerland.

*No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.
†Department of Orthopaedics, University of Zurich, Balgrist, 8008 Zurich, Switerland.
‡Departments of Orthopaedics (S. M. L.) and Radiology (H. M. H.), Hôpital Cantonal, 1708 Fribourg, Switzerland.
 
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+Anteroposterior radiograph of the right shoulder, showing a subcoracoid dislocation.
 
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+Selective right axillary arteriogram (late arterial phase), showing active bleeding from a partial tear in the proximal part of the anterior circumflex artery (large arrow) with residual antegrade flow. There is retrograde filling of the avulsed posterior circumflex artery (small arrow) through anastomoses between its descending branches and the ascending branches of the deep brachial artery (broken arrow).
 
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+Anteroposterior radiograph, made eighteen months after the injury, showing no evidence of avascular changes.
 
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+Figs. 4-A, 4-B, and 4-C: Magnetic resonance images of the right shoulder, made eighteen months after the injury. The normal bone-marrow signal intensities on the images exclude the possibility of osteonecrosis. Fig. 4-A: T1-weighted image.
 
 
A fifty-seven-year-old man, who was right-hand dominant and had no history of problems related to the shoulder, sustained a closed anterior subcoracoid dislocation of the right glenohumeral joint as the result of a fall (Fig. 1). Immediately after the injury, the patient had pain and numbness in the entire hand and forearm and was unable to flex or extend the elbow or to move the digits. On clinical testing, the flexors of the wrist and digits as well as the intrinsic muscles of the hand did not contract. Active flexion of the elbow was possible against gravity but not against manual resistance. There was numbness over the deltoid muscle and no clinical activity of that muscle.
With use of a Kocher maneuver and intravenous sedation, a closed reduction was achieved without difficulty. A large, tense, painful swelling developed in the anterior axillary fold and extended over the cephalad part of the chest. The right arm became edematous, although the radial pulse at the wrist remained palpable. Complete paralysis of flexion and extension of the elbow developed in addition to the neurological deficits noted before the reduction.
Selective axillary angiography was performed, with the patient sedated, approximately one hour after the manipulative reduction. It revealed complete rupture of the posterior circumflex artery as well as active bleeding from the anterior circumflex artery. There was evidence of some antegrade filling of the arcuate artery from the anterior circumflex artery (Fig. 2). The lesions of the circumflex arteries appeared isolated to their point of origin off the axillary artery, and there was no evidence of intimal dissection within the axillary artery.
In the operating room, three hours after the manipulative reduction, an exploration was performed with the patient under general anesthesia. The hematoma was evacuated, and the axillary sheath was explored through a deltopectoral approach with detachment of the short head of the biceps brachii and the pectoralis minor from the coracoid process as well as partial detachment of the insertion of the tendon of the pectoralis major. The anterior and posterior circumflex arteries were both found to be completely ruptured close to their origin from the axillary artery. The infraclavicular brachial plexus was explored, and the components were noted to be bruised but intact. There was a rupture of the supraspinatus tendon, which was thought to be consistent with the trauma as the edges of the tendon were actively bleeding. The tendon was repaired with a transosseous suture technique. A trough was created at the exact transition from the cartilage of the humeral head to the greater tuberosity. The cancellous bone that formed the base of the trough was bleeding but to a lesser degree than is usually observed during standard repairs of the rotator cuff. Because of the age of the patient and the risk of additional operative trauma, a decision was made to ligate the anterior and posterior circumflex arteries rather than to reconstruct them. The potential risk of subsequent avascular necrosis of the humeral head was recognized.
A magnetic resonance image made one month after the operation revealed no findings that were consistent with the development of avascular necrosis of the humeral head. Four months after the injury, standard radiographic assessment of the glenohumeral joint demonstrated osteoporosis of the head and the greater tuberosity, suggestive of vascular perfusion throughout the proximal aspect of the humerus. All signs of the plexopathy resolved by six months after the operation.
Radiographic examination at eighteen months showed the proximal aspect of the humerus to be normal (Fig. 3). Magnetic resonance images made at the same time revealed no signs of avascular disturbance of the humeral head (Figs. 4-A, 4-B, and 4-C). The patient had normal motion of the shoulder, with only mild limitation of strength when he used the right arm behind and above the head.
Injury of the axillary artery has been described in association with acute traumatic anterior dislocation of the glenohumeral joint3,5,7,8,11 and subsequent to manipulation of the joint1,4,9. Jardon et al. described two cases of rupture of the axillary artery immediately proximal to the circumflex branches. Brown and Navigato described a patient who had intimal rupture of the distal third of the axillary artery immediately distal to the subscapular branch but stated that most ruptures of the main vessels occurred at the origin of the subscapular and circumflex branches. This observation was confirmed by Curr. No subsequent observations of the vascularity of the humeral head were made in these studies3,5, and we did not find any discussion on the vascular status of the proximal part of the humerus after injury of the axillary artery or its branches.
The anterolateral branch of the anterior circumflex artery enters the humeral head at the proximal end of the lateral aspect of the intertubercular groove and supplies most of the epiphysis as the intraosseous arcuate artery2,6,10,12. The posterior circumflex artery directly contributes to the vascularity of the humeral head through posteromedial branches2,6 and branches from the rotator cuff vessels12. Vascular injection studies by one of us (C. G.) and colleagues6 demonstrated that the arcuate artery supplies almost the entire epiphysis, with the posterior circumflex artery contributing the most sizable anastomoses to the arcuate artery in a dense rete on and within the greater tuberosity and on the joint capsule. Other anastomotic vessels (such as from the thoracoacromial artery) contribute to the vascularization of the humeral head by communicating with the anterolateral branch of the anterior circumflex artery immediately before its entrance into the humeral head or by anastomosis with the posterior circumflex artery dorsally. These vessels are therefore of potential importance in the blood supply of the humeral head when the circumflex vessels are interrupted6. The findings of this study6 also refuted a report12 that suggested that the humeral head receives vascular perfusion from the rotator cuff vessels; there was no evidence that the humeral head received any vascular perfusion from the rotator cuff.
With both circumflex arteries interrupted and the extraosseous anastomotic network compromised, the present case report brings to light the clinical relevance of the intraosseous anastomoses provided for the most part by the deep brachial artery6. The absence of avascular necrosis suggests that these anastomoses are relevant, a finding that is corroborated by our observation that minimally displaced fractures of the anatomical neck may be complicated by avascular necrosis.
Bertrand, J. C.; Maestro, M.; Pequignot, J. P.; and |and |Mouiel, J.: Les complications vasculaires des luxations antérieures fermées de l'epaule. Ann. chir.,36: 329-333, 1981.36329  1981 
 
Brooks, C. H.; Revell, W. J.; and |and |Heatley, F. W.: Vascularity of the humeral head after proximal humeral fractures. An anatomical cadaver study. J. Bone and Joint Surg.,75-B(1): 132-136, 1993.75-B(1)132  1993 
 
Brown, F. W., and |and |Navigato, W. J.: Rupture of the axillary artery and brachial plexus palsy associated with anterior dislocation of the shoulder. Report of a case with successful vascular repair. Clin. Orthop.,60: 195-199, 1968.60195  1968  [PubMed]
 
Calvet, J.; Leroy, M.; and |and |Lacroix, L.: Luxations de l'épaule et lésions vasculaires. J. chir.,58: 337-346, 1942.58337  1942 
 
Curr, J. F.: Rupture of the axillary artery complicating dislocation of the shoulder. Report of a case. J. Bone and Joint Surg.,52-B(2): 313-317, 1970.52-B(2)313  1970 
 
Gerber, C.; Schneeberger, A. G.; and |and |Vinh, T.-S.: The arterial vascularization of the humeral head. An anatomical study. J. Bone and Joint Surg.,72-A: 1486-1494, Dec. 1990.72-A1486  1990 
 
Henson, G. F.: Vascular complications of shoulder injuries. A report of two cases. J. Bone and Joint Surg.,38-B(2): 528-531, 1956.38-B(2)528  1956 
 
Jardon, O. M.; Hood, L. T.; and |and |Lynch, R. D.: Complete avulsion of the axillary artery as a complication of the shoulder dislocation. J. Bone and Joint Surg.,55-A: 189-192, Jan. 1973.55-A189  1973 
 
Kirker, J. R.: Dislocation of the shoulder complicated by rupture of the axillary vessels. Report of a case. J. Bone and Joint Surg.,34-B(1): 72-73, 1952.34-B(1)72  1952 
 
Laing, P. G.: The arterial supply of the adult humerus. J. Bone and Joint Surg.,38-A: 1105-1116, Oct. 1956.38-A1105  1956 
 
Lev-El, A.; Adar, R.; and |and |Rubinstein, Z.: Axillary artery injury in erect dislocation of the shoulder. J. Trauma,21: 323-325, 1981.21323  1981  [PubMed][CrossRef]
 
Moseley, H. F., and |and |Goldie, I.: The arterial pattern of the rotator cuff of the shoulder. J. Bone and Joint Surg.,45-B(4): 780-789, 1963.45-B(4)780  1963 
 

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Anchor for JumpAnchor for Jump
+Anteroposterior radiograph of the right shoulder, showing a subcoracoid dislocation.
Anchor for JumpAnchor for Jump
+Selective right axillary arteriogram (late arterial phase), showing active bleeding from a partial tear in the proximal part of the anterior circumflex artery (large arrow) with residual antegrade flow. There is retrograde filling of the avulsed posterior circumflex artery (small arrow) through anastomoses between its descending branches and the ascending branches of the deep brachial artery (broken arrow).
Anchor for JumpAnchor for Jump
+Anteroposterior radiograph, made eighteen months after the injury, showing no evidence of avascular changes.
Anchor for JumpAnchor for Jump
+Figs. 4-A, 4-B, and 4-C: Magnetic resonance images of the right shoulder, made eighteen months after the injury. The normal bone-marrow signal intensities on the images exclude the possibility of osteonecrosis. Fig. 4-A: T1-weighted image.
Bertrand, J. C.; Maestro, M.; Pequignot, J. P.; and |and |Mouiel, J.: Les complications vasculaires des luxations antérieures fermées de l'epaule. Ann. chir.,36: 329-333, 1981.36329  1981 
 
Brooks, C. H.; Revell, W. J.; and |and |Heatley, F. W.: Vascularity of the humeral head after proximal humeral fractures. An anatomical cadaver study. J. Bone and Joint Surg.,75-B(1): 132-136, 1993.75-B(1)132  1993 
 
Brown, F. W., and |and |Navigato, W. J.: Rupture of the axillary artery and brachial plexus palsy associated with anterior dislocation of the shoulder. Report of a case with successful vascular repair. Clin. Orthop.,60: 195-199, 1968.60195  1968  [PubMed]
 
Calvet, J.; Leroy, M.; and |and |Lacroix, L.: Luxations de l'épaule et lésions vasculaires. J. chir.,58: 337-346, 1942.58337  1942 
 
Curr, J. F.: Rupture of the axillary artery complicating dislocation of the shoulder. Report of a case. J. Bone and Joint Surg.,52-B(2): 313-317, 1970.52-B(2)313  1970 
 
Gerber, C.; Schneeberger, A. G.; and |and |Vinh, T.-S.: The arterial vascularization of the humeral head. An anatomical study. J. Bone and Joint Surg.,72-A: 1486-1494, Dec. 1990.72-A1486  1990 
 
Henson, G. F.: Vascular complications of shoulder injuries. A report of two cases. J. Bone and Joint Surg.,38-B(2): 528-531, 1956.38-B(2)528  1956 
 
Jardon, O. M.; Hood, L. T.; and |and |Lynch, R. D.: Complete avulsion of the axillary artery as a complication of the shoulder dislocation. J. Bone and Joint Surg.,55-A: 189-192, Jan. 1973.55-A189  1973 
 
Kirker, J. R.: Dislocation of the shoulder complicated by rupture of the axillary vessels. Report of a case. J. Bone and Joint Surg.,34-B(1): 72-73, 1952.34-B(1)72  1952 
 
Laing, P. G.: The arterial supply of the adult humerus. J. Bone and Joint Surg.,38-A: 1105-1116, Oct. 1956.38-A1105  1956 
 
Lev-El, A.; Adar, R.; and |and |Rubinstein, Z.: Axillary artery injury in erect dislocation of the shoulder. J. Trauma,21: 323-325, 1981.21323  1981  [PubMed][CrossRef]
 
Moseley, H. F., and |and |Goldie, I.: The arterial pattern of the rotator cuff of the shoulder. J. Bone and Joint Surg.,45-B(4): 780-789, 1963.45-B(4)780  1963 
 
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