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Case Reports   |    
Odontoid Fracture Associated with a Pharyngeal Tear A Case Report*
Anton Kathrein, M.D.; Alexander Genelin, M.D.; Ravi Gupta, M.D.; Christoph Rangger, M.D.
View Disclosures and Other Information
Investigation performed at Universitätsklinik für Unfallchirurgie, Innsbruck, Austria
*No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.
Universitätsklinik für Unfallchirurgie, Anichstrasse 35, A-6020 Innsbruck, Austria. E-mail address: akathrein@yahoo.com (A. Kathrein).

The Journal of Bone & Joint Surgery.  2000; 82:1154-1154 
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Pharyngeal perforation is a rare and serious injury. Infection of the surrounding anatomical structures may occur due to contamination of the oral cavity. Therefore, immediate diagnosis and subsequent treatment appear to be essential.
We present the case of a patient who sustained an odontoid fracture that was associated with a pharyngeal perforation. The pharyngeal injury was not noted initially, although the clinical findings, preoperative radiographs, and computed tomography scans suggested a pharyngeal tear. To our knowledge, such an injury has not been reported previously. Nevertheless, in a patient with a fracture of the cervical spine and bleeding from the mouth, pharyngeal perforation should be considered.
 
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+Fig. 1:Lateral radiograph of the cervical spine, made after reduction of the odontoid fracture and application of a stiff collar, showing soft-tissue swelling (small arrows) and air (large arrows) in the retropharyngeal region.
 
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+Fig. 2:Preoperative axial computed tomography scan, made at the level of the odontoid fracture, showing air (arrow) in the prevertebral soft tissue.
 
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+Fig. 3:Anteroposterior and lateral radiographs of the upper cervical spine, made four years after anterior screw fixation of the odontoid process, showing solid osseous healing of the fracture in the anatomical position.
 
A thirty-eight-year-old man sustained head trauma following a mountain-bike accident. The patient sought medical care one day after the injury. He reported bleeding from the nose and mouth and complained of increasing neck pain. Clinical evaluation revealed no neurological deficits. Anteroposterior and lateral radiographs of the cervical spine showed an anteriorly displaced type-II fracture of the odontoid process1. The initial treatment included closed reduction of the fracture and immobilization of the neck with a stiff collar (Fig. 1Fig. 1). The next day, the fracture was stabilized with two cannulated titanium lag screws through an anteromedial retropharyngeal approach2,4. Immediately after the operation, when the stomach tube was removed, bleeding from the mouth was detected. Inspection of the oral cavity revealed a linear median tear, four centimeters long, in the nasopharynx. No abnormalities were seen upon further inspection of the ear, nose, and throat region. Initially, the presumed etiology of the tear was intraoperative iatrogenic damage of the pharyngeal wall. However, reexamination of the preoperative radiographs and computed tomography scans revealed retropharyngeal swelling and an abnormal presence of air in the prevertebral soft tissue (Fig. 1 and Fig. 2).
Immediately after recognition of the pharyngeal tear, the patient was managed with administration of cephalosporins and insertion of another stomach tube for feeding. Inspection of the pharyngeal wound two days later revealed no evidence of local infection. Therefore, the pharyngeal wound was closed operatively with resorbable interrupted sutures through a transoral approach. The stomach tube was removed three days later. Cephalosporins were administered for fifteen days. The subsequent healing of the pharyngeal wall and the operative wound was uneventful. The odontoid fracture healed within three months. After six months, the patient had a full range of motion of the neck and had no difficulties with swallowing or phonation. Four years after the operation, the patient was without complaints and radiographs showed solid osseous healing of the fracture (Fig. 3-A and Fig. 4).
Pharyngoesophageal injuries in patients with cervical spine trauma are rare. Such injuries have been reported after blunt trauma and after penetrating injuries caused by knives, gunshots, and missiles3. Injuries of the pharynx may be complicated by cervical abscess, spondylodiscitis, mediastinitis, cervical fistula, esophageal stricture, or formation of diverticula. To our knowledge, an odontoid fracture associated with a pharyngeal tear has not been reported previously. In the case of our patient, the exact mechanism of the injury was not determined retrospectively. Nevertheless, severe instability of the upper cervical spine should be considered when perforation of the pharyngeal wall and odontoid fracture have occurred. The open injury of the pharynx was not noted during the initial clinical evaluation of our patient, and therefore the odontoid fracture was treated operatively through an anterior retropharyngeal approach. Even during the intubation and the initial operation, the injury was not detected. An early diagnosis in this case would not have been difficult had we been aware of the injury. If the pharyngeal perforation had been diagnosed preoperatively, we might have postponed the fracture fixation until the tear had healed. Alternatively, we might have treated the injury with a dorsal atlantoaxial arthrodesis or with nonoperative measures such as the application of a halo device. Pharyngoesophageal injuries in patients with cervical spine trauma have been treated with extraoral feeding, exploration of the neck, or operative repair of the esophagus3. Anterior cervical discectomy and arthrodesis with metal implants in patients with pharyngoesophageal injuries frequently have been associated with cervical osteomyelitis3. Therefore, alternative methods of stabilization of cervical spine fractures have been suggested3.
Although the pharyngeal perforation in our patient was not noted initially, osseous healing occurred, without infection, after early anterior stabilization.
Bleeding from the mouth and nose following head trauma, as was reported by our patient, should have led to an immediate and careful examination of the ear, nose, and throat region. Retropharyngeal air was present and could have been detected on lateral radiographs or computed tomography scans. Nevertheless, the abnormal presence of air was not noted because of concentration on the fracture site rather than on soft-tissue changes.
A cervical spine fracture that is associated with bleeding from the mouth and nose should alert the physician to the possibility of a pharyngeal injury. Careful examination of radiographs and computed tomography scans and immediate inspection of the oral cavity will help to establish the correct diagnosis early enough to provide appropriate treatment.
Anderson, L. D., and D'Alonzo, R. T.: Fractures of the odontoid process of the axis. J. Bone and Joint Surg.,56-A: 1663-1674, Dec 1974.56-A1663  1974 
 
Böhler, J.: Anterior stabilization for acute fractures and non-unions of the dens. J. Bone and Joint Surg.,64-A: 18-27, Jan 1982.64-A18  1982 
 
English, G. M.; Hsu, S. F.; Edgar, R.; and Gibson-Eccles, M.: Oesophageal trauma in patients with spinal cord injury. Paraplegia,30: 903-912, 1992.30903  1992  [PubMed]
 
Nakanishi, T.; Sasaki, T.; Tokita, N.; and Hirabayashi, K.: Internal fixation for the odontoid fracture. Orthop. Trans.,6: 176, 1982.6176  1982 
 

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Anchor for JumpAnchor for Jump
+Fig. 1:Lateral radiograph of the cervical spine, made after reduction of the odontoid fracture and application of a stiff collar, showing soft-tissue swelling (small arrows) and air (large arrows) in the retropharyngeal region.
Anchor for JumpAnchor for Jump
+Fig. 2:Preoperative axial computed tomography scan, made at the level of the odontoid fracture, showing air (arrow) in the prevertebral soft tissue.
Anchor for JumpAnchor for Jump
+Fig. 3:Anteroposterior and lateral radiographs of the upper cervical spine, made four years after anterior screw fixation of the odontoid process, showing solid osseous healing of the fracture in the anatomical position.
Anderson, L. D., and D'Alonzo, R. T.: Fractures of the odontoid process of the axis. J. Bone and Joint Surg.,56-A: 1663-1674, Dec 1974.56-A1663  1974 
 
Böhler, J.: Anterior stabilization for acute fractures and non-unions of the dens. J. Bone and Joint Surg.,64-A: 18-27, Jan 1982.64-A18  1982 
 
English, G. M.; Hsu, S. F.; Edgar, R.; and Gibson-Eccles, M.: Oesophageal trauma in patients with spinal cord injury. Paraplegia,30: 903-912, 1992.30903  1992  [PubMed]
 
Nakanishi, T.; Sasaki, T.; Tokita, N.; and Hirabayashi, K.: Internal fixation for the odontoid fracture. Orthop. Trans.,6: 176, 1982.6176  1982 
 
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