Background: The challenge of cost-efficiency
is maintaining the quality of medical care while reducing costs and
eliminating unnecessary practices. The purpose of this investigation
was to evaluate the cost and effectiveness of routine pathological
examination of surgical specimens from patients undergoing primary
total hip or knee replacement for the treatment of osteoarthritis.
Methods: Effectiveness was assessed by comparing
clinical and pathological diagnoses associated with 1234 consecutive
primary total joint replacements (471 hip and 763 knee replacements)
performed between 1992 and 1995 in one hospital in patients with
the clinical diagnosis of osteoarthritis. Clinical and pathological
diagnoses were considered concordant if they agreed, discrepant
if they differed without a resultant change in patient management,
and discordant if they differed with a resultant change in patient
management. Cost identification was performed by determining charges,
reimbursement, and costs in 1998-adjusted American dollars for both
total hip and total knee replacement. The cost per health-effect
was determined by calculating the cost per discrepant and discordant
diagnosis.
Results: The prevalence of concordant diagnoses
was 97.6 percent (1205 of 1234) (95 percent confidence interval,
96.6 to 98.4 percent), the prevalence of discrepant diagnoses was
2.3 percent (twenty-eight of 1234) (95 percent confidence interval,
1.4 to 3.1 percent), and the prevalence of discordant diagnoses
was 0.1 percent (one of 1234) (95 percent confidence interval, 0.1
to 0.3 percent). The cost per discrepant diagnosis was $4383, and
the cost per discordant diagnosis was $122,728.
Conclusions: Routine pathological examination
of surgical specimens from patients undergoing primary total hip
or knee replacement because of the clinical diagnosis of osteoarthritis
had limited cost-effectiveness at our hospital due to the low prevalence of
findings that altered patient management.