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Gait and Function After Intra-Articular Arthrodesis of the Hip in Adolescents*
L. A. KAROL, M.D.†; S. E. HALLIDAY, M.S.†; P. GOURINENI, M.D.‡
View Disclosures and Other Information
Investigation performed at the Texas Scottish Rite Hospital for Children, Dallas, Texas
*No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.
†Texas Scottish Rite Hospital for Children, 2222 Welborn Street, Dallas, Texas 75219.
‡3000 North Halsted Street, Suite 611, Chicago, Illinois 60657.

The Journal of Bone & Joint Surgery.  2000; 82:561-561 
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Abstract

Background: Patients who have had a hip arthrodesis have been reported to have pain in the back and the knee due to an altered gait. There is little information about the specific compensatory mechanisms that are adopted when walking. The purpose of this study was to objectively define gait adaptations after an arthrodesis of the hip and to correlate the kinematic findings with pain and other patient outcomes.

Methods: Nine patients who had had an arthrodesis of the hip at an average age of thirteen years and five months (range, ten years and nine months to sixteen years and eleven months) were evaluated with gait analysis and muscle strength-testing and completed a questionnaire related to pain and function. The average duration of follow-up was eight years and ten months (range, two years and one month to thirteen years and ten months). The frequency of the postoperative visits varied. Seven patients were adults at the time of the study and were called back specifically for the study.

Results: All patients had decreased cadence and step lengths. The kinematic findings included decreased dorsiflexion of the ipsilateral ankle, hyperextension of the ipsilateral knee during the stance phase, and a tendency toward increased genu valgum during gait. In normal gait, there is no genu varum or valgum during the stance phase.

The patients had an average (and standard deviation) of 7 ± 4 degrees of genu valgum. Pelvic and lumbar motion in the sagittal plane was excessive in all patients. Strength-testing revealed clinically relevant weakness in the ipsilateral quadriceps in all patients, with a difference of more than 20 percent between the two extremities in six patients. The gastrocnemius-soleus muscle was stronger on the side with the fused hip in six patients.

The questionnaire, designed by Harris in 1969 and completed by the patients at the time of the gait analysis, revealed back pain in seven patients. The questionnaire was administered only once. The functional outcome as measured with use of the same questionnaire worsened as the duration of follow-up increased.

Conclusions: The gait analysis showed excessive motion in the lumbar spine and the ipsilateral knee in all nine patients. This abnormal motion led to pain as the duration of follow-up increased, and all patients who had been followed for four or more years after the arthrodesis complained of back pain. We hypothesized that excessive motion for an extended duration can lead to back pain. The preferred position of the hip for the arthrodesis was 20 to 25 degrees of flexion, neutral abduction-adduction, and neutral rotation.

Figures in this Article
    Hip arthrodesis remains the most viable operative treatment for the active adolescent who has severe degenerative disease of the hip. Although total hip arthroplasty is performed in patients who have juvenile rheumatoid arthritis, it is not currently advocated for children who have unilateral joint destruction and are otherwise normal. The goal of the arthrodesis is to alleviate pain in the hip by eliminating motion, but this has been reported to produce abnormal pressures on the lumbar spine and the ipsilateral knee2,3,12. Benaroch et al.2 performed a preliminary study assessing cadence parameters and function in thirteen patients who had undergone an arthrodesis of the hip and found that single-limb support was of shorter duration on the affected side.
    The purpose of the current study was to further analyze the gait of patients who had had an arthrodesis of the hip, with particular attention paid to motion at the knee and the lumbar spine, and to correlate the gait-analysis findings with the radiographic findings and the clinical symptoms.
     
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    +Fig. 1-A:Anteroposterior radiograph of the pelvis, made immediately after an arthrodesis and subtrochanteric osteotomy.
     
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    +Fig. 1-B:Anteroposterior radiograph made at the time of the final follow-up, showing fusion of the hip and healing of the femoral osteotomy.
     
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    +Fig. 2:Graph showing sagittal plane kinematics of the ankle and the knee. The range of normal motion is represented between the dotted lines; the values for the fused hip, by the thick black solid line; and the values for the contralateral extremity, by the thin gray solid line. Note the decreased dorsiflexion (DF) of the ankle on the side with the hip fusion during the stance phase and the hyperextension of the ipsilateral knee at the time of the initial contact. PF = plantar flexion, HC = heel contact, and TO = toe-off.
     
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    +Fig. 3:Graph showing sagittal plane kinematics of the pelvis and the lumbar spine. The range of normal motion is represented between the dotted lines, and the values for the fused hip are represented by the solid line. Note the increases in anterior pelvic tilt, pelvic range of motion, lumbar lordosis, and lumbar range of motion in the patients with a fused hip. HC = heel contact, and TO = toe-off.
     
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    +Fig. 4:Graph showing transverse plane kinematics of the pelvis and the lumbar spine. The range of normal motion is represented between the dotted lines, and the values for the fused hip are represented by the solid line. There is increased pelvic and lumbar rotation in the patients with a fused hip. HC = heel contact, and TO = toe-off.
     
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    +Fig. 5:Graph showing the severity of the back pain versus the time after the arthrodesis. There is a trend for back pain to increase with increasing durations of follow-up.
     
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    +Fig. 6:Photograph showing knee hyperextension following an arthrodesis of the left hip.
     
    Anchor for JumpAnchor for Jump:  TABLE IClinical and Demographic Information on the Nine Patients Who Had an Arthrodesis of the Hip
    CaseGenderDiagnosisComplicationsAdditional OperationsAge at Op. (yrs. + mos.)Age at Follow-up(yrs. + mos.)Durat. of Follow-up(yrs. + mos.)
    1FIdiopathic chondrolysis12 + 614 + 6  2 + 1
    2FAvascular necrosis secondary to slipped capital femoral epiphysisFracture through site of fusionIlizarov external fixation11 + 017 + 8  6 + 9
    3MAvascular necrosis secondary to slipped capital femoral epiphysisIpsilateral inter- trochanteric femoral fractureOpen reduction and internal fixation, Ilizarov external fixation for limb-length discrepancy, 1/92-5/9215 + 125 + 0    9 + 11
    4FIdiopathic chondrolysis11 + 8  14 + 11  3 + 4
    5MLegg-Calv笐erthes diseaseIlizarov external fixation for limb-length discrepancy, 4/90-9/9010 + 924 + 7  13 + 10
    6MAvascular necrosis secondary to femoral neck fractureIpsilateral distal femoral fracture and ipsilateral ankle fracture  15 + 11  27 + 1112 + 0
    7MAvascular necrosis secondary to slipped capital femoral epiphysis15 + 527 + 912 + 4
    8MAvascular necrosis secondary to slipped capital femoral epiphysis13 + 424 + 111 + 3
    9MSeptic dislocation of hip  16 + 1125 + 3  8 + 3
    We reviewed the medical records of nineteen patients who had had an arthrodesis of the hip between January 1980 and December 1996 and had had a minimum of two years of follow-up. Nine patients agreed to participate in the study. (Six patients could not be located, two had had a hip replacement, one had osteogenesis imperfecta, and one was seriously ill.) The study was approved by the institutional review board, and all patients or their legal guardians signed informed-consent forms.
    The operative technique was identical in all patients; it consisted of an intra-articular arthrodesis with the hip in the position of maximal contact between the femoral head and the acetabulum, a subtrochanteric osteotomy, and immobilization in a spica cast as described by Mowery et al.8 (Fig. 1-A and Fig. 1-B). The position of the hip was verified with direct visualization fluoroscopy.
    There were six male patients and three female patients in the study group (Table I). The average age at the time of the operation was thirteen years and five months (range, ten years and nine months to sixteen years and eleven months), and the average age at the time of follow-up was twenty-two years and four months (range, fourteen years and six months to twenty-seven years and eleven months). The average duration of follow-up was eight years and ten months (range, two years and one month to thirteen years and ten months).
    The preoperative diagnoses included slipped capital femoral epiphysis with avascular necrosis in four patients; idiopathic chondrolysis in two patients; and avascular necrosis following a femoral neck fracture, Legg-Calv笐erthes disease, and a septic hip dislocation in one patient each.
    Three patients sustained a total of four fractures (a fracture through the fusion site, an ipsilateral intertrochanteric femoral fracture, and ipsilateral distal femoral and ankle fractures) after the arthrodesis. The distal femoral fracture was treated with a cast for four months; the fracture through the fusion site was treated with Ilizarov external fixation for six months; and the ipsilateral intertrochanteric femoral fracture, sustained after a motor-vehicle accident fifteen months postoperatively, was treated with open reduction and internal fixation followed by Ilizarov external fixation because of limb-length discrepancy. In addition, one patient was treated with Ilizarov fixation because of limb-length discrepancy.
    A physical examination was performed to assess the position of the fused hip and to measure the range of motion of the knee. Since this examination was done postoperatively, we could assess only the position in which the hip had been fused and could not determine the best position for the arthrodesis. Limb-length discrepancy was quantified with use of blocks to level the posterior iliac spine with the patient in the standing position. Scanograms were not obtained; thus, any contribution of pelvic asymmetry to the limb-length discrepancy was not excluded. The circumference of the thigh was measured bilaterally at a point ten centimeters proximal to the level of the superior pole of the patella. Knee stability was evaluated clinically and was described either as present or as decreased with or without an end point in the medial, lateral, and anteroposterior directions.
    An anteroposterior radiograph of the pelvis was made on the day of testing. Because the purpose of the current study was to determine the final result and not to follow the patients sequentially over time, radiographs were made at various times after the operation but not as part of the study. All patients had instrumented gait analysis and isokinetic muscle strength-testing of the knee and the ankle. Both extremities were tested only at the time of the latest follow-up visit.
    Kinematic data were gathered as each patient walked at a self-selected speed along a fifteen-meter runway; the volume of the space for calibration was 2.5 meters. Each walk was videotaped simultaneously in the frontal and sagittal planes. Thirty-eight reflective markers were placed on the body to track motion during gait of twelve linked segments: the head, the arms, the thoracic spine, the lumbar spine, the pelvis, the thighs, the legs, and the feet. Three-dimensional kinematic data were recorded with a six-camera sixty-hertz VICON system (Oxford Metrics, Oxford, England). Data were recorded for each extremity of each patient for four representative cycles. Lumbar, hip, knee, and ankle-joint angles were calculated in the sagittal, coronal, and transverse planes with use of BodyBuilder software (Oxford Metrics). These angles included lumbar flexion and extension, right and left lateral tilt, and axial rotation; pelvic anterior and posterior tilt, right and left obliquity, and axial rotation; hip flexion and extension, adduction and abduction, and internal and external rotation; knee flexion and extension, varus and valgus, and internal and external rotation; ankle plantar flexion and dorsiflexion and internal and external rotation; and foot progression angle. The three-dimensional relationships between the movements of the pelvis and the lumbar spine during walking were evaluated on the basis of the model described by Whittle and Levine17. Hip, knee, and ankle-joint centers were located with use of the methods described by Davis et al.5. Cadence, velocity, step length, and the percent of the gait cycle spent in single and double-limb support were calculated. Maximum and minimum values for joint angles were identified with use of custom software written in the movement-science laboratory at the Texas Scottish Rite Hospital for Children. A computer was used to determine maximum and minimum values in order to improve precision and eliminate human error.
    Five normal subjects who had never had an orthopaedic procedure had gait analysis with use of the thirty-eight-marker model, and the data were analyzed with the BodyBuilder software. These data then were compared with those in reports on lumbar spine motion in the literature4,17 in order to verify our model. We did not perform similar comparisons for motion of the pelvis, hips, knees, and ankles because that data has been well documented10. We used standard data that are employed by gait-analysis laboratories, and we were confident that the data on our patients with hip fusion could be compared reliably with the aforementioned normal data. In contrast, there is much less data on lumbar spine motion; three-dimensional motion, calculated with use of photogrammetry, has been reported in only two studies3,17, to our knowledge. We chose to duplicate the methods of Whittle and Levine17 because those authors indicated that markers attached to lightweight wands and not directly to the skin allowed for more accurate and reliable data. Our data on the normal subjects showed ranges and patterns of motion similar to those reported by Whittle and Levine.
    Isokinetic muscle strength was measured with a Cybex-II machine (Ronkonkoma, New York); the knee flexors and extensors were tested with the patient in the seated position, which required allowing the patient to recline slightly to accommodate the fused hip. The ankle plantar flexors and dorsiflexors were tested with the patient in the prone position, with allowances made for the flexed position of the hip. The quadriceps and hamstrings were tested at 60 degrees per second, and the anterior tibialis and gastrocnemius-soleus were tested at 30 degrees per second. The peak torque per body weight was selected from one of five trials. All testing was performed by an experienced exercise physiologist. Asymmetry of more than 20 percent between the two sides was considered clinically relevant13.
    All nine patients completed a modified Harris hip-score questionnaire7. The Harris hip score, as described by Harris in 1969, allots a maximum of 100 points, 91 of which are related to pain and function and 9, to range of motion and the presence of deformity. We omitted the areas of the score pertaining to motion and deformity and did not ask our patients about their use of public transportation. This left a possible maximum score of 90 points, similar to that used in previous studies of patients who had had a hip arthrodesis2,9. We used the Harris hip score because it had been used by Benaroch et al.2 and we wanted to compare our data with theirs.
    Anteroposterior radiographs were reviewed to assess the healing at the site of the fusion. Adduction and abduction of the extremity were measured as the angle between the perpendicular to the horizontal line connecting the inferior parts of the teardrops of both acetabuli and a line drawn down the anatomical shaft of the femur beginning at the site of the subtrochanteric osteotomy. The perpendicular line is drawn from the junction of the line along the shaft and the horizontal line. We selected the inferior ends of the teardrops because they were seen on all of the radiographs and because the triradiate cartilage was closed as these patients were adults or older teenagers. The top of the iliac crest was not used as a marker because it could have been distorted by harvest of the bone graft.
    Statistical analysis of the data was performed with t tests to determine the difference in the range of motion between the control subjects and the patients who had had an arthrodesis. Pearson correlation was used to determine the relationship between the position of the fused hip and the dependent variables, which included the range of motion and the maximum and minimum values for joint angles of the lumbar spine, pelvis, hip, knee, and ankle in the sagittal, coronal, and transverse planes. Pearson correlation also was used to determine if there were any relationships between the clinical data, including pain, and the motion data or the duration of follow-up.
    At the time of the examination in the gait laboratory, the position of the fused hip in the nine patients was an average (and standard deviation) of 26 ± 10 degrees (range, 10 to 45 degrees) of flexion, 1 ± 6 degrees of abduction (range, 7 degrees of abduction to 10 degrees of adduction), and 6 ± 7 degrees of internal rotation (range, 18 degrees of internal rotation to 0 degrees of external rotation). The additional procedures on the hip (Cases 2, 3, and 5) and the fractures sustained after the arthrodesis (Cases 2, 3, and 6) may have influenced the ultimate position of the fusion.
    Limb-length discrepancy averaged 2.7 centimeters (range, 1.0 to 5.0 centimeters). The extremity on the side with the fused hip was shorter in all patients. All patients had muscle atrophy in the thigh, which ranged from 0.5 to 4.0 centimeters (average, 2.6 centimeters). Knee laxity was present in eight patients. All eight had laxity in the mediolateral plane, and seven also had anteroposterior laxity. However, all eight had good end points to stress. Passive range of motion of the ipsilateral knee was notable for hyperextension in all patients.
    Force-plate evaluation, performed with the patient standing with both feet on the ground, revealed that six patients put more than 50 percent of their weight on the extremity on the side with the fused hip. As the limb on that side was shorter in all patients, this may have simply been an attempt to maintain a plantigrade position of the feet. Nonetheless, the patients did not avoid weight-bearing on the side with the fused hip.
    Cadence parameters were identical to those of the patients in the studies by Benaroch et al.2 and Waters et al.16. Five of the patients in the current study had been included in the study by Benaroch et al. at the time of an earlier follow-up. The cadence of the patients who had a fused hip averaged 110 steps per minute compared with 116 steps per minute for the normal subjects; this difference was significant (p < 0.05). The walking velocity of the patients who had a fused hip averaged 1.1 0.1 meters per second compared with 1.3 meters per second for the normal subjects; this difference was also significant (p < 0.05). Step lengths, which averaged 0.6 meter, were reduced symmetrically in the group with a fused hip compared with that (0.66 meter) in the normal group. The patients spent slightly less time in single-limb stance on the fused side than on the contralateral side (35 and 39 percent of the gait cycle, respectively).
    Kinematic findings included decreased dorsiflexion of the ipsilateral ankle during the stance phase in all nine patients; only one patient had an ankle that was in frank equinus during stance (Fig. 2). Knee flexion-extension curves in the sagittal plane showed hyperextension on the ipsilateral side during the stance phase in eight patients. By the time of toe-off, all patients had knee flexion that was greater than normal on the fused side (Fig. 2). The knee has a greater dynamic range of motion during gait to accommodate for the lack of hip motion in the forward movement of the body over the stance-phase foot and also to assist in clearance of the foot since the hip cannot flex and pull the foot off the ground as swing is initiated. The dynamic range of motion correlated with the increased passive range of motion and passive hyperextension seen in all nine patients (r = 0.78, p < 0.05). Additionally, knee hyperextension tended to increase with increasing flexion of the fused hip (r = 0.76, p < 0.05). The eight patients with medial and lateral joint laxity had excessive genu valgum during gait. Normally, the knee has minimal rotation during gait. The patients had an average of 7± 4 degrees of genu valgum. All nine patients exhibited excessive rotation through the ipsilateral knee during gait (p < 0.05).
    The average pelvic and lumbar ranges of motion for the five normal subjects were very similar to the values reported by Crosbie et al.4 and by Whittle and Levine17. In the sagittal plane, the pelvis tilts posteriorly at the same time as the hip is in maximal flexion, and it tilts anteriorly during single-limb stance. In the coronal plane, the pelvis normally drops slightly during the swing phase. In the transverse plane, the pelvis rotates internally slightly as the swinging limb advances and it rotates externally in the stance phase.
    The average pelvic motion in the sagittal plane in the nine patients was 12.8 ± 2 degrees (Fig. 3), which was greater than the normal value of 3.5 ± 1.5 degrees over one gait cycle; this difference was significant (p < 0.05). Hips that were fused in more flexion were associated with more anterior pelvic tilt (r = 0.81, p < 0.05). (One hip was fused in 45 degrees of flexion; one, in 35 degrees; one, in 30 degrees; two, in 25 degrees; three, in 20 degrees; and one, in 10 degrees. No hip was fused in extension.) Normal anterior pelvic tilt is approximately 10 degrees, whereas the patients had between 18 and 42 degrees of anterior pelvic tilt. No patient had an increase in pelvic motion in the coronal plane, but six had greater-than-normal pelvic rotation in the transverse plane. The normal range of pelvic rotation in the transverse plane during gait is 10.1 ± 2.5 degrees. The average range of pelvic rotation in the transverse plane was 13.0 ± 2 degrees (range, 9 to 19 degrees) in the patients (Fig. 4). In the current study, one standard deviation of normal was considered to be beyond normal limits.
    The position of the lumbar spine is quite variable, but motion in the sagittal plane is minimal in normal subjects, as was noted both in the current study and in published series4,17. Lumbar motion averaged 7.5± 2 degrees in the nine patients. All patients had greater-than-normal lumbar motion (range, 5.7 to 9.8 degrees) in the sagittal plane (Fig. 3). Lumbar lordosis tended to increase with increased flexion of the fused hip (r = 0.74, p < 0.05).
    We determined the degree of kinematic lumbar lordosis on the basis of the motion data and chose the average of the lumbar flexion-extension graph as the degree of lordosis. Lumbar tilt in the coronal plane was not increased in the patients, whereas lumbar rotation was increased, averaging 12 ± 3 degrees compared with 10 degrees in the normal subjects (Fig. 4). This 2-degree difference was not significant; however, the increase in lumbar spinal motion in the sagittal and transverse planes is clinically relevant since we believe that it explains why patients have back pain after an arthrodesis of the hip. If the hip cannot move during gait, the spine compensates with abnormally increased motion, which, over time, leads to pain. Six of the nine patients had increased lumbar rotation. Patients in whom the hip was fused in more flexion did not exhibit more pelvic and lumbar rotation when advancing the limb compared with patients in whom the hip was fused in more relative extension (r = 0.78, p < 0.05).
    Isokinetic muscle-strength testing showed that six of the nine patients had stronger plantar flexors in the ipsilateral ankle (p < 0.05); however, the ipsilateral quadriceps was weaker in all nine, with an average difference between the involved and uninvolved sides of 18 percent (range, 3 to 40 percent). Six patients had asymmetry of more than 20 percent in the isokinetic strength of the quadriceps. Hamstring weakness with a difference between sides of more than 20 percent was present in five patients. The gastrocnemius-soleus muscle was stronger on the side with the fused hip in six patients. Comparisons were not made with the extremities of the normal subjects as strength is extremely variable both among individuals and in relation to gender and age.
    Seven patients complained of back pain, which averaged 6.1 points on a scale of 0 to 10 points. The same seven patients also noted pain in the ipsilateral knee, which averaged 3.1 points on a scale of 0 to 10 points. Two patients rated the pain in the ipsilateral knee as 1 point; one, as 2 points; one, as 3 points; and three, as 5 points. The two patients who did not have pain in the back or the knee were the youngest patients in the series; they were less than fifteen years old at the time of the latest follow-up, and they also had the shortest duration of follow-up.
    According to the Harris scale, two patients had no hip pain, three had slight discomfort, one had mild pain, and three had moderate pain. One patient had pain in the contralateral hip, and two had pain in the contralateral knee. All patients could walk at least one mile (1.6 kilometers), although one often used a cane. Only one adult patient was unemployed, although three patients thought that the fused hip limited their employment choices.
    The modified Harris hip score averaged 69.5 points (range, 47 to 90 points) of a maximum of 90 points. We used the rating scale of Benaroch et al.2 to classify the results of the questionnaire. According to this scale, 82 to 90 points indicated an excellent result; 73 to 81 points, a good result; 64 to 72 points, a fair result; and less than 64 points, a poor result. One patient had an excellent result, four had a good result, one had a fair result, and three had a poor result. There was a trend toward worsening of the modified Harris hip score with increasing durations of follow-up (r = 0.76).
    Pearson correlation coefficients demonstrated a relationship between abduction of the fused hip and knee instability (r = 0.76, p < 0.05). There was a good correlation between the severity of back pain and the duration of follow-up after the arthrodesis (r = 0.75, p < 0.05) (Fig. 5).
    We found that back pain was present in seven of nine patients who had a fused hip. The two patients who reported no back pain were both fourteen years old at the time of the study and had only two and three years of follow-up. The onset of the back pain was much earlier than has been reported in most series3,12, including an earlier series from this institution2. Callaghan et al.3 evaluated twenty-eight patients at an average of thirty-five years after an arthrodesis of the hip. The average age at the time of the arthrodesis was twenty-five years (range, ten to fifty-eight years). Sixty percent of their patients had back pain within twenty-five years after the arthrodesis. Those authors used their own questionnaire to evaluate the patients but did not include it in their paper. Roberts and Fetto12 evaluated ten patients at an average of eight and a half years (range, one year and six months to forty-four years) after a hip arthrodesis. The average age at the time of the operation was thirty-four years (range, twenty-three years and six months to seventy-eight years). Back pain was present in four of their patients, and pain in the ipsilateral knee was noted in two.
    Sponseller et al.15 studied fifty-three patients who were thirty-five years old or less at the time of an arthrodesis. At an average of thirty-eight years (range, twenty to fifty-four years), 57 percent had some low-back pain. Those authors devised their own scale to evaluate the patients. A careful review of their study shows that only 16 percent of their patients had no back pain and an additional 27 percent had rare episodes of pain.
    Benaroch et al.2 studied thirteen patients who had an average age of twenty-two years (range, nineteen to twenty-seven years) at the time of the study and fifteen years at the time of the arthrodesis. Ten patients had occasional back pain, and seven had pain in the ipsilateral knee. Barnhardt and Stiehl1 reported back pain in all six of their patients at an average of twelve years (range, five to twenty-eight years).
    The correlation between the duration of follow-up and back pain in the current study suggests that pain develops earlier than has traditionally been thought. We noted an earlier onset of back pain because our patients were younger and more active and therefore were more likely to have symptoms in association with activities. We did not use the same scales as those employed by other authors with the exception of Benaroch et al.2. We asked our patients to quantify their pain numerically because it is possible that a patient who is able to participate fully in activities and who has only occasional pain would not report pain otherwise. We found no correlation between the degree of flexion or adduction of the fused hip and the presence of back pain. Others have found that hip fusion in between 25 and 30 degrees of flexion and in neutral to slight adduction led to fewer symptoms related to the lumbar spine6,11. Price and Lovell11 studied fourteen children at an average of five years (range, one to ten years) after a hip arthrodesis and reported no back pain in any child and knee pain in only one child. Only four patients were followed for more than five years. Those authors recommended an optimum position of 30 degrees of flexion, neutral adduction, and neutral rotation; however, they did not attempt to correlate the subjective result with the position of the fused hip. In the current study, no patient had pain during the first seven years after the operation.
    On the basis of our data, it is possible to provide a biomechanical explanation for the increasing prevalence of back pain. We documented abnormally increased motion of the pelvis, which correlated with increased motion of the lumbar spine. Motions in the sagittal and transverse planes were the most abnormal. It follows that increased flexion and extension of the pelvis and, therefore, of the lumbar spine is necessary to advance the body forward in gait, replacing the role of hip motion. Increased pelvic and lumbar rotation are also recruited to help advance the extremity. The increased lumbar and pelvic motion comes at a price, with low-back pain as the result.
    Seven of our patients complained of pain in the ipsilateral knee, and we documented increased laxity and hyperextension of the knee in all nine patients (Fig. 6). Kinematically, the pattern of knee motion was abnormal, with an increased dynamic range of motion in the sagittal plane. Since the iliopsoas is ineffective in pulling the foot on the side with the fused hip off the ground in the early swing phase, the knee must hyperflex to initiate swing and then to allow for foot clearance during the swing phase. Although abduction of the fused hip was linked to increasing knee instability, a series of nine patients is insufficient for us to precisely define the optimal position for hip fusion so as to protect the knee. Clearly, increased abduction or adduction will result in abnormal varus and valgus moments across the knee in the stance phase and will place it at risk for instability or degenerative arthritis due to asymmetrical loads6. Gore et al.6 stated that more than 10 degrees of adduction should be avoided, since hips that were fused in more adduction caused the patient to walk slowly and with greater irregularity in forward progression. Sponseller et al.15 found that 10 degrees of adduction of the fused hip led to greater valgus angulation at the knee and that less than 10 degrees led to genu varum.
    Muscular support of the ipsilateral knee is compromised by weakness of the quadriceps and the hamstrings. Despite weakness of the knee, the plantar flexors of the ipsilateral ankle were stronger on isokinetic testing in the present study. As the iliopsoas and the superficial hip flexors are nonfunctional in a patient with a fused hip, the gastrocnemius-soleus must push the extremity off the ground and into the swing phase. Neutral rotation of the extremity is important in order to place the ankle and gastrocnemius-soleus in optimal alignment for push-off.
    We did not collect metabolic data on oxygen consumption or oxygen cost in this group of patients. Waters et al.16 measured oxygen consumption in an older group of eleven adult patients who had had a hip arthrodesis at an average age of forty-six years (range, twenty-three to fifty-seven years) and found a 32 percent increase in oxygen consumption compared with that in normal adults. The average interval between the operation and the testing was 7.5 years (range, 1.5 to thirty years). The average rate of energy expenditure was 14.9 milliliters per kilogram of body weight per minute compared with 12.1 milliliters per kilogram of body weight per minute for normal individuals. The heart rate of the patients who had had a hip arthrodesis averaged 112 beats per minute compared with ninety-nine beats per minute for the controls. The oxygen cost averaged 0.223 milliliter per kilogram per meter for the group that had had a hip arthrodesis compared with 0.166 milliliter per kilogram per meter for patients who had had an ankle arthrodesis. Waters et al. concluded that patients who had had a hip arthrodesis were 53 percent as efficient during gait as the normal controls.
    Limb-length discrepancy remains an issue for patients who have a fused hip. Benaroch et al.2 correlated back pain, quadriceps weakness, and cadence abnormalities with limb-length inequality. If epiphyseodesis of the distal aspect of the femur of the unaffected extremity is possible on the basis of skeletal age, then this procedure can be performed to decrease or correct the discrepancy. Benaroch et al. recommended equalization for patients who had a limb-length discrepancy of more than two centimeters. Gore et al.6 found that limb-length discrepancy was associated with a decrease in cadence and step length and emphasized the importance of minimizing shortening on the side of the fusion. Price and Lovell11 did not make any specific recommendations, but several of their patients used a shoe-lift and one patient had an epiphyseodesis. All of our patients had less ankle dorsiflexion on the side with the hip fusion in the stance phase, which is a strategy used to reduce the rise and fall of the center of mass by children with limb-length inequality14. Attention should be given to equalization of limb lengths when feasible in patients with a fused hip. The utility of prescribing a shoe-lift was not evaluated in the current study.
    In general, we found that patients with less flexion at the fusion site walked better than those with increased hip flexion. Less pelvic anterior tilt and less sagittal plane motion were seen and the lumbar spine moved less in the transverse plane if the hip was less flexed. However, patients in whom the hip was fused in more extension complained of difficulty in sitting. Videotapes of these patients made during the transition from sitting to standing revealed thoracolumbar kyphosis when the patient was seated. There does not appear to be a position of flexion that allows easy sitting and pain-free walking; therefore, on the basis of these preliminary data, we recommend the commonly used position of moderate flexion of the hip (20 to 25 degrees). Since knee instability was correlated with hip abduction, a position of neutral hip abduction-adduction at the time of the final follow-up, after postoperative adduction drift has occurred, should be attempted.
    Our findings are disturbing, as abnormal lumbar spine motion was evident in all nine patients and back pain was already present in seven patients between seven and fourteen years after the arthrodesis. Only the two patients who had been followed for two and three years did not have back pain, but they demonstrated abnormal kinematic movement of the lumbar spine. However, there are patients for whom no other treatment can provide pain relief. On the basis of our data, we believe that if an osteotomy can relieve pain in an adolescent with hip-joint destruction then it may be reasonable to consider performing this procedure instead of an arthrodesis of the hip. Increased pelvic and lumbar motion and abnormal knee motion are seen in young adults following an arthrodesis of the hip performed during adolescence. This abnormal motion predisposes the patient to back pain over time. The onset of back symptoms occurred earlier in our patients than has been noted previously. Arthrodesis should remain a last resort in the treatment of an adolescent who has severe degeneration of the hip joint. The position of choice for an arthrodesis of the hip is 20 to 25 degrees of flexion, neutral adduction-abduction, and neutral rotation.
    Note: The authors acknowledge the assistance of Cecilia Concha, B.S., in data acquisition and model development, and Cindy Smith, B.S., in patient testing.
    Barnhardt, T., and Stiehl, J. B.: Hip fusion in young adults. Orthopedics, 19: 303-306, 1996. 
     
    Benaroch, T. E.; Richards, B. S.; Haideri, N.; and Smith, C.: Intermediate follow-up of a simple method of hip arthrodesis in adolescent patients. J. Pediat. Orthop., 16: 30-36, 1996. 
     
    Callaghan, J. J.; Brand, R. A.; and Pedersen, D. R.: Hip arthrodesis. A long-term follow-up. J. Bone and Joint Surg., 67-A: 1328-1335, Dec. 1985. 
     
    Crosbie, J.; Vachalathiti, R.; and Smith, R.: Patterns of spinal motion during walking. Gait and Posture, 5: 6-12, 1997. 
     
    Davis, R. B.; Ounpuu, S.; Tyburski, D.; and Gage, J. R.: A gait analysis data collection and reduction technique. Human Movement Sci., 10: 575-587, 1991. 
     
    Gore, D. R.; Murray, M. P.; Sepic, S. B.; and Gardner, G. M.: Walking patterns of men with unilateral surgical hip fusion. J Bone Joint Surg, 57-A: 759-765, Sept. 1975. 
     
    Harris, W. H.: Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. J Bone Joint Surg, 51-A: 737-755, June 1969. 
     
    Mowery, C. A.; Houkom, J. A.; Roach, J. W.; and Sutherland, D. H.: A simple method of hip arthrodesis. J. Pediat. Orthop., 6: 7-10, 1986. 
     
    Murrell, G. A. C., and Fitch, R. D.: Hip fusion in young adults. Using a medial displacement osteotomy and cobra plate. Clin. Orthop., 300: 147-154, 1994. 
     
    Perry, J.: Gait Analysis: Normal and Pathological Function. New York, McGraw-Hill, 1992. 
     
    Price, C. T., and Lovell, W. W.: Thompson arthrodesis of the hip in children. J Bone Joint Surg, 62-A: 1118-1123, Oct. 1980. 
     
    Roberts, C. S., and Fetto, J. F.: Functional outcome of hip fusion in the young patient. Follow-up study of 10 patients. J. Arthroplasty, 5: 89-96, 1990. 
     
    Sapega, A. A.: Current concepts review. Muscle performance evaluation in orthopaedic practice. J. Bone and Joint Surg., 72-A: 1562-1574, Dec. 1990. 
     
    Song, K. M.; Halliday, S. E.; and Little, D. G.: The effect of limb-length discrepancy on gait. J. Bone and Joint Surg., 79-A: 1690-1698, Nov. 1997. 
     
    Sponseller, P. D.; McBeath, A. A.; and Perpich, M.: Hip arthrodesis in young patients. A long-term follow-up study. J Bone Joint Surg, 66-A: 853-859, July 1984. 
     
    Waters, R. L.; Barnes, G.; Husserl, T.; Silver, L.; and Liss, R.: Comparable energy expenditure after arthrodesis of the hip and ankle. J Bone Joint Surg, 70-A: 1032-1037, Aug. 1988. 
     
    Whittle, M. W., and Levine, D.: Measurement of lumbar lordosis as a component of clinical gait analysis. Gait and Posture, 5: 101-107, 1997. 
     

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    +Fig. 1-A:Anteroposterior radiograph of the pelvis, made immediately after an arthrodesis and subtrochanteric osteotomy.
    Anchor for JumpAnchor for Jump
    +Fig. 1-B:Anteroposterior radiograph made at the time of the final follow-up, showing fusion of the hip and healing of the femoral osteotomy.
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    +Fig. 2:Graph showing sagittal plane kinematics of the ankle and the knee. The range of normal motion is represented between the dotted lines; the values for the fused hip, by the thick black solid line; and the values for the contralateral extremity, by the thin gray solid line. Note the decreased dorsiflexion (DF) of the ankle on the side with the hip fusion during the stance phase and the hyperextension of the ipsilateral knee at the time of the initial contact. PF = plantar flexion, HC = heel contact, and TO = toe-off.
    Anchor for JumpAnchor for Jump
    +Fig. 3:Graph showing sagittal plane kinematics of the pelvis and the lumbar spine. The range of normal motion is represented between the dotted lines, and the values for the fused hip are represented by the solid line. Note the increases in anterior pelvic tilt, pelvic range of motion, lumbar lordosis, and lumbar range of motion in the patients with a fused hip. HC = heel contact, and TO = toe-off.
    Anchor for JumpAnchor for Jump
    +Fig. 4:Graph showing transverse plane kinematics of the pelvis and the lumbar spine. The range of normal motion is represented between the dotted lines, and the values for the fused hip are represented by the solid line. There is increased pelvic and lumbar rotation in the patients with a fused hip. HC = heel contact, and TO = toe-off.
    Anchor for JumpAnchor for Jump
    +Fig. 5:Graph showing the severity of the back pain versus the time after the arthrodesis. There is a trend for back pain to increase with increasing durations of follow-up.
    Anchor for JumpAnchor for Jump
    +Fig. 6:Photograph showing knee hyperextension following an arthrodesis of the left hip.
    Anchor for JumpAnchor for Jump:  TABLE IClinical and Demographic Information on the Nine Patients Who Had an Arthrodesis of the Hip
    CaseGenderDiagnosisComplicationsAdditional OperationsAge at Op. (yrs. + mos.)Age at Follow-up(yrs. + mos.)Durat. of Follow-up(yrs. + mos.)
    1FIdiopathic chondrolysis12 + 614 + 6  2 + 1
    2FAvascular necrosis secondary to slipped capital femoral epiphysisFracture through site of fusionIlizarov external fixation11 + 017 + 8  6 + 9
    3MAvascular necrosis secondary to slipped capital femoral epiphysisIpsilateral inter- trochanteric femoral fractureOpen reduction and internal fixation, Ilizarov external fixation for limb-length discrepancy, 1/92-5/9215 + 125 + 0    9 + 11
    4FIdiopathic chondrolysis11 + 8  14 + 11  3 + 4
    5MLegg-Calv笐erthes diseaseIlizarov external fixation for limb-length discrepancy, 4/90-9/9010 + 924 + 7  13 + 10
    6MAvascular necrosis secondary to femoral neck fractureIpsilateral distal femoral fracture and ipsilateral ankle fracture  15 + 11  27 + 1112 + 0
    7MAvascular necrosis secondary to slipped capital femoral epiphysis15 + 527 + 912 + 4
    8MAvascular necrosis secondary to slipped capital femoral epiphysis13 + 424 + 111 + 3
    9MSeptic dislocation of hip  16 + 1125 + 3  8 + 3
    Barnhardt, T., and Stiehl, J. B.: Hip fusion in young adults. Orthopedics, 19: 303-306, 1996. 
     
    Benaroch, T. E.; Richards, B. S.; Haideri, N.; and Smith, C.: Intermediate follow-up of a simple method of hip arthrodesis in adolescent patients. J. Pediat. Orthop., 16: 30-36, 1996. 
     
    Callaghan, J. J.; Brand, R. A.; and Pedersen, D. R.: Hip arthrodesis. A long-term follow-up. J. Bone and Joint Surg., 67-A: 1328-1335, Dec. 1985. 
     
    Crosbie, J.; Vachalathiti, R.; and Smith, R.: Patterns of spinal motion during walking. Gait and Posture, 5: 6-12, 1997. 
     
    Davis, R. B.; Ounpuu, S.; Tyburski, D.; and Gage, J. R.: A gait analysis data collection and reduction technique. Human Movement Sci., 10: 575-587, 1991. 
     
    Gore, D. R.; Murray, M. P.; Sepic, S. B.; and Gardner, G. M.: Walking patterns of men with unilateral surgical hip fusion. J Bone Joint Surg, 57-A: 759-765, Sept. 1975. 
     
    Harris, W. H.: Traumatic arthritis of the hip after dislocation and acetabular fractures: treatment by mold arthroplasty. An end-result study using a new method of result evaluation. J Bone Joint Surg, 51-A: 737-755, June 1969. 
     
    Mowery, C. A.; Houkom, J. A.; Roach, J. W.; and Sutherland, D. H.: A simple method of hip arthrodesis. J. Pediat. Orthop., 6: 7-10, 1986. 
     
    Murrell, G. A. C., and Fitch, R. D.: Hip fusion in young adults. Using a medial displacement osteotomy and cobra plate. Clin. Orthop., 300: 147-154, 1994. 
     
    Perry, J.: Gait Analysis: Normal and Pathological Function. New York, McGraw-Hill, 1992. 
     
    Price, C. T., and Lovell, W. W.: Thompson arthrodesis of the hip in children. J Bone Joint Surg, 62-A: 1118-1123, Oct. 1980. 
     
    Roberts, C. S., and Fetto, J. F.: Functional outcome of hip fusion in the young patient. Follow-up study of 10 patients. J. Arthroplasty, 5: 89-96, 1990. 
     
    Sapega, A. A.: Current concepts review. Muscle performance evaluation in orthopaedic practice. J. Bone and Joint Surg., 72-A: 1562-1574, Dec. 1990. 
     
    Song, K. M.; Halliday, S. E.; and Little, D. G.: The effect of limb-length discrepancy on gait. J. Bone and Joint Surg., 79-A: 1690-1698, Nov. 1997. 
     
    Sponseller, P. D.; McBeath, A. A.; and Perpich, M.: Hip arthrodesis in young patients. A long-term follow-up study. J Bone Joint Surg, 66-A: 853-859, July 1984. 
     
    Waters, R. L.; Barnes, G.; Husserl, T.; Silver, L.; and Liss, R.: Comparable energy expenditure after arthrodesis of the hip and ankle. J Bone Joint Surg, 70-A: 1032-1037, Aug. 1988. 
     
    Whittle, M. W., and Levine, D.: Measurement of lumbar lordosis as a component of clinical gait analysis. Gait and Posture, 5: 101-107, 1997. 
     
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