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The Anatomy of the Lateral Femoral Cutaneous Nerve, with Special Reference to the Harvesting of Iliac Bone Graft*
Yasuaki Murata, M.D.†; Kazuhisa Takahashi, M.D.†; Masatsune Yamagata, M.D.†; Yutaka Shimada, M.D.†; Hideshige Moriya, M.D.†
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Investigation performed at the Department of Orthopaedic Surgery and the First Department of Anatomy, School of Medicine, Chiba University, Chiba, Japan
*No benefits in any form have been received or will be received from a commercial party related directly or indirectly to the subject of this article. No funds were received in support of this study.
†Department of Orthopaedic Surgery (Y. M., K. T., M. Y., and H. M.) and First Department of Anatomy (Y. S.), School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba 260-8677, Japan. Please address requests for reprints to Yasuaki Murata. E-mail address: murata@anatlab1.m.chiba-u.ac.jp (Yasuaki Murata).

The Journal of Bone & Joint Surgery.  2000; 82:746-746 
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Autogenous bone graft is frequently obtained from the anterior part of the ilium; however, many studies have shown that the harvesting of autogenous iliac bone graft carries the risk of meralgia paresthetica2,4-6,8,9. Although the lateral femoral cutaneous nerve usually emerges from the lateral border of the psoas major muscle and crosses the ilium as it runs toward the anterior superior iliac spine, its course can vary1,3,7. We investigated the anatomy of the lateral femoral cutaneous nerve, particularly as it relates to the harvesting of autogenous anterior iliac bone graft.
The position of the lateral femoral cutaneous nerve was identified on both sides of the pelvis in 108 formalin-embalmed cadavera from Japanese individuals (sixty-four men and forty-four women) who had been sixty to ninety-seven years old at the time of death. Eleven of the 216 nerves could not be included because of tumor invasion, leaving 205 nerves available for study. The lateral femoral cutaneous nerve was identified after opening of the anterior abdominal wall and evisceration of the abdomen. The psoas major muscle was removed, and the second and third lumbar nerves were identified. The lateral femoral cutaneous nerve was evaluated according to (1) the position of the nerve in relation to the anterior superior iliac spine at the point where the nerve crossed over the iliac crest or under the inguinal ligament, and (2) the course of the nerve across the anterior surface of the iliacus muscle. In cases in which two or more branches of the lateral femoral cutaneous nerve were observed, the most lateral one was measured.
The position of the nerve in relation to the anterior superior iliac spine varied. We categorized each nerve as type A (crossing over the iliac crest more than two centimeters posterior to the anterior superior iliac spine), type B (crossing over the iliac crest within two centimeters posterior to the anterior superior iliac spine), type C (crossing at the anterior superior iliac spine), or type D (crossing under the inguinal ligament and anterior to the anterior superior iliac spine) (Fig. 1).
The course of the nerve also varied; some nerves ran straight across the iliacus muscle, whereas others followed a convex or a concave curve. We examined the lateral femoral cutaneous nerve at a point five centimeters posterior to the anterior superior iliac spine and categorized it as type 1 (crossing the iliacus muscle within three centimeters of the iliac crest) or type 2 (crossing the iliacus muscle more than three centimeters away from the iliac crest). The results are summarized in Table I.
Many studies have shown that the harvesting of autogenous iliac bone graft is associated with a risk of lateral femoral cutaneous nerve injury, even if attention is paid to this danger2,4-6,8,9. Such an injury may occur because of the variability of the anatomical course and the location of the lateral femoral cutaneous nerve, as demonstrated in this study.
The variation of the course of the lateral femoral cutaneous nerve suggests that some risk of injury is difficult to avoid during an operative approach to the iliac crest. The findings of the present study suggest that 9.9 percent of the nerves (including all of the type-1 nerves as well as the type-2A nerves) may have been at risk for injury if the patient had undergone harvesting of anterior iliac bone. Therefore, all patients should be informed of the possibility of lateral femoral cutaneous nerve injury before an iliac crest bone graft is harvested.
 
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+Fig. 1:Illustrations showing the four positions of the lateral femoral cutaneous nerve in relation to the anterior superior iliac spine. Type-A nerves crossed over the iliac crest more than two centimeters posterior to the anterior superior iliac spine (a), type-B nerves crossed over the iliac crest within two centimeters posterior to the anterior superior iliac spine (b), type-C nerves crossed at the anterior superior iliac spine (c), and type-D nerves crossed under the inguinal ligament and anterior to the anterior superior iliac spine (d).
Aszmann, O. C., Dellon, E. S.,Dellon, A. L.. Anatomical course of the lateral femoral cutaneous nerve and its susceptibility to compression and injury. Plast. and Reconstr. Surg.,100: 600-604. 1997;100600  1997 
 
Banwart, J. C., Asher, M. A.,Hassanein, R. S.. Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine,20: 1055-1060. 1995;201055  1995  [PubMed]
 
Dibenedetto, L. M., Lei, Q., Gilroy, A. M., Hermey, D. C., Marks, S. C., Jr.,Page, D. W.. Variations in the inferior pelvic pathway of the lateral femoral cutaneous nerve: implications for laparoscopic hernia repair. Clin. Anat.,9: 232-236. 1996;9232  1996  [PubMed]
 
Kurz, L. T., Garfin, S. R.,Booth, R. E., Jr.. Harvesting autogenous iliac bone grafts. A review of complications and techniques. Spine,14: 1324-1331. 1989;141324  1989  [PubMed]
 
Laurie, S. W., Kaban, L. B., Mulliken, J. B.,Murray, J. E.. Donor-site morbidity after harvesting rib and iliac bone. Plast. and Reconstr. Surg.,73: 933-938. 1984;73933  1984 
 
Massey, E. W.. Meralgia paresthetica secondary to trauma of bone graft. J. Trauma,20: 342-343. 1980;20342  1980  [PubMed]
 
Nathan, H.. Gangliform enlargement on the lateral cutaneous nerve of the thigh. Its significance in the understanding of the etiology of meralgia paresthetica. J. Neurosurg.,17: 843-849. 1960;17843  1960  [PubMed]
 
Summers, B. N.,Eisenstein, S. M.. Donor site pain from the ilium. A complication of lumbar spine fusion. J Bone Joint Surg,71-B(4): 677-680. 1989;71-B(4)677  1989 
 
Weikel, A. M.,Habal, M. B.. Meralgia paresthetica: a complication of iliac bone procurement. Plast. and Reconstr. Surg.,60: 572-574. 1977;60572  1977 
 

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+Fig. 1:Illustrations showing the four positions of the lateral femoral cutaneous nerve in relation to the anterior superior iliac spine. Type-A nerves crossed over the iliac crest more than two centimeters posterior to the anterior superior iliac spine (a), type-B nerves crossed over the iliac crest within two centimeters posterior to the anterior superior iliac spine (b), type-C nerves crossed at the anterior superior iliac spine (c), and type-D nerves crossed under the inguinal ligament and anterior to the anterior superior iliac spine (d).
Aszmann, O. C., Dellon, E. S.,Dellon, A. L.. Anatomical course of the lateral femoral cutaneous nerve and its susceptibility to compression and injury. Plast. and Reconstr. Surg.,100: 600-604. 1997;100600  1997 
 
Banwart, J. C., Asher, M. A.,Hassanein, R. S.. Iliac crest bone graft harvest donor site morbidity. A statistical evaluation. Spine,20: 1055-1060. 1995;201055  1995  [PubMed]
 
Dibenedetto, L. M., Lei, Q., Gilroy, A. M., Hermey, D. C., Marks, S. C., Jr.,Page, D. W.. Variations in the inferior pelvic pathway of the lateral femoral cutaneous nerve: implications for laparoscopic hernia repair. Clin. Anat.,9: 232-236. 1996;9232  1996  [PubMed]
 
Kurz, L. T., Garfin, S. R.,Booth, R. E., Jr.. Harvesting autogenous iliac bone grafts. A review of complications and techniques. Spine,14: 1324-1331. 1989;141324  1989  [PubMed]
 
Laurie, S. W., Kaban, L. B., Mulliken, J. B.,Murray, J. E.. Donor-site morbidity after harvesting rib and iliac bone. Plast. and Reconstr. Surg.,73: 933-938. 1984;73933  1984 
 
Massey, E. W.. Meralgia paresthetica secondary to trauma of bone graft. J. Trauma,20: 342-343. 1980;20342  1980  [PubMed]
 
Nathan, H.. Gangliform enlargement on the lateral cutaneous nerve of the thigh. Its significance in the understanding of the etiology of meralgia paresthetica. J. Neurosurg.,17: 843-849. 1960;17843  1960  [PubMed]
 
Summers, B. N.,Eisenstein, S. M.. Donor site pain from the ilium. A complication of lumbar spine fusion. J Bone Joint Surg,71-B(4): 677-680. 1989;71-B(4)677  1989 
 
Weikel, A. M.,Habal, M. B.. Meralgia paresthetica: a complication of iliac bone procurement. Plast. and Reconstr. Surg.,60: 572-574. 1977;60572  1977 
 
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