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Case Reports   |    
Idiopathic Heterotopic Ossification Within the Tibial Nerve A Case Report
Seiji Yoshida, MD, PhD; Hirofumi Taira, MD; Masashi Kataoka, MD, PhD; Chikahiro Takita, MD; Hiroshi Tsumura, MD, PhD
The Journal of Bone & Joint Surgery.  2002; 84:1442-1444 
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Extract

Heterotopic ossification has been reported to occur following burns, musculoskeletal trauma, and tetanus and in association with metabolic and neurologic disorders. Heterotopic ossification is found most commonly in the muscles, and histopathologically identical lesions have been described in tendons, subcutaneous fat, ligaments, fasciae, aponeuroses, and joint capsules 1 . Heterotopic ossification can also cause clinically relevant peripheral nerve entrapment 2-4 . Heterotopic ossification or calcification within a peripheral nerve is a rare lesion and may arise in association with neurofibroma 5 , leprosy 6 , CREST syndrome (calcinosis, Raynaud phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia) 7 , diabetic neuropathy8-10, and chronic renal failure11.
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