Extract
Hemophilia is an X-linked disorder characterized by a tendency to
hemorrhage due to the lack of production of clotting factors VIII and IX. The
worldwide prevalence of hemophilia A and B are one in 10,000 and one in
25,000,
respectively1.Hemarthrosis is common in patients with hemophilia. Large joints, such as
the knee, ankle, and elbow, are particularly prone to recurrent bleeding.
Bleeding may occur preferentially into a particular joint, which may become
the so-called target joint.