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Quadriparesis Complicating Atlantoaxial Subluxation and Ossification of the Posterior Longitudinal Ligament in a Patient with Rheumatoid ArthritisA Case Report
Osamu Shirado, MD1; Hirotaka Azuma, MD2; Naoki Takeda, MD3; Akio Minami, MD2
1 Department of Orthopaedic Surgery, Saitama Medical School, Moroyama, Saitama 350-0495, Japan. E-mail address: oshirado@m4.dion.ne.jp
2 Department of Orthopaedic Surgery, Hokkaido University Graduate School of Medicine, Kita-15 Nishi-7, Kita-ku, Sapporo 060-8638, Japan
3 Department of Health Sciences, Hokkaido University School of Medicine, Kita-12 Nishi-5, Kita-ku, Sapporo 060-0812, Japan
The Journal of Bone & Joint Surgery.  2005; 87:1354-1357  doi:10.2106/JBJS.D.02083
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Extract

Rheumatoid arthritis frequently involves the cervical spine, especially the atlantoaxial joint, often resulting in atlantoaxial subluxation. In series ranging in size from seventy-three to 333 patients, 25% to 60% of patients with rheumatoid arthritis had this lesion1. Atlantoaxial subluxation sometimes causes devastating cervical myelopathy in these patients.Ossification of the posterior longitudinal ligament appears as an abnormal radiopacity along the posterior margins of the vertebral bodies as seen on lateral radiographs. It also may cause spinal cord compression, resulting in myelopathy2. Tsukimoto was probably the first to describe ossification of the posterior longitudinal ligament in Japan, on the basis of autopsy findings, in 19603. Since then, many reports of this disease in both the cervical and the thoracic spine have been published in Japan. Tsuyama and Nakanishi et al. reported that the prevalence of radiographically demonstrated ossification of the posterior longitudinal ligament was 2% (121 of 6034) and that this value increased to 11% (eleven of 104) among patients over the age of sixty years in Japan4,5. Only a limited number of cases of ossification of the posterior longitudinal ligament have been reported among non-Japanese individuals6,7. Satomi and Hirabayashi reported that ossification of the posterior longitudinal ligament was observed on the cervical radiographs of approximately 2.1% of 1000 outpatients in east Asian countries, including Japan, compared with 0.2% of 854 subjects at the Mayo Clinic and 0.6% of 490 subjects in Hawaii2.
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