Extract
Brown tumors are locally destructive bone lesions caused by rapid
osteoclastic bone resorption due to severe
hyperparathyroidism1.
For years, brown tumors have been considered to be characteristic of primary
hyperparathyroidism. However, brown tumors also have been reported to occur in
patients with severe hyperparathyroidism secondary to chronic renal
failure2-4,
especially those on long-term hemo-dialysis. Hypocalcemia, hyperphosphatemia,
and vitamin-D deficiency are the basic characteristics of chronic renal
failure associated with secondary hyperparathyroidism.