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Detection of Posttraumatic Cartilage Injury Using Quantitative T1rho Magnetic Resonance ImagingA Report of Two Cases with Arthroscopic Findings
Jesus Lozano, BS1; Xiaojuan Li, PhD1; Thomas M. Link, MD1; Marc Safran, MD2; Sharmila Majumdar, PhD1; C. Benjamin Ma, MD2
1 Musculoskeletal and Quantitative Imaging Research Group (MQIR), Department of Radiology, University of California at San Francisco, 185 Berry Street, Suite 350, San Francisco, CA 94107
2 Department of Orthopaedic Surgery, University of California at San Francisco, 500 Parnassus Avenue, MU 320W, San Francisco, CA 94143. E-mail address for C.B. Ma: maben@orthosurg.ucsf.edu
The Journal of Bone & Joint Surgery.  2006; 88:1349-1352  doi:10.2106/JBJS.E.01051
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Extract

Cartilage injuries following trauma are a common problem and can lead to premature, secondary osteoarthritis. Standard magnetic resonance imaging techniques can detect cartilage breakdown associated with morphological changes, such as decreases in cartilage thickness and volume, but it cannot detect early changes of the cartilage matrix. There is a need for a noninvasive method with which to diagnose articular cartilage abnormalities at early stages in order to initiate early treatment prior to the macroadaptive changes seen on radiographs.
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