JBJS | Invasive Group-A Streptococcal Infection in an Allograft Recipient: A Case Report

The Journal of Bone & Joint Surgery, Volume 89, Issue 9

Case Reports | September 01, 2007

Invasive Group-A Streptococcal Infection in an Allograft Recipient: A Case Report

Ellen H. Lee, MD¹; Dayna Ferguson, MD¹; Daniel Jernigan, MD, MPH²; Melissa Greenwald, MD³; Timothy Coté, MD³; Jon E. Bos, MPH⁴; Jeannette Guarner, MD⁵; Sherif Zaki, MD, PhD⁵; Anne Schuchat, MD¹; Bernard Beall, PhD¹; Arjun Srinivasan, MD²

¹ Epidemic Intelligence Service, Career Development Division, Office of Workforce and Career Development (E.H.L. and D.F.) and Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases (E.H.L., A.S., B.B.), Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop C-23, Atlanta, GA 30333
² Epidemiology Section, Division of Healthcare Quality Promotion, National Center for Infectious Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop A-35, Atlanta, GA 30333. E-mail address for A. Srinivasan: beu8@cdc.gov
³ Center for Biologics Evaluation and Research, United States Food and Drug Administration, 1401 Rockville Pike, Suite 200N, Rockville, MD 20852-1448
⁴ Oklahoma State Department of Health, 1000 N.E. 10th Street, Oklahoma City, OK 73117-1299
⁵ Infectious Disease Pathology Activity, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road, Mailstop G-32, Atlanta, GA 30333

The Journal of Bone & Joint Surgery. 2007; 89:2044-2047 doi:10.2106/JBJS.F.01594

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Extract

Each year, approximately 1.5 million musculoskeletal allografts are distributed for transplantation1. Allograft tissues offer advantages over autografts, such as smaller surgical incisions, reduced operative times, and lack of donor-site morbidity2. A disadvantage of allografts is the potential, albeit low, for disease transmission. Recent investigations have implicated a variety of allografts in the transmission of several microorganisms3-7. We investigated the occurrence of invasive group-A streptococcal disease in a musculoskeletal allograft recipient.

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Topics

streptococcal infections ; allografting ; tissue donors

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These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.

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