The ability of nanostructures to elicit altered cell behaviors, including
cell adhesion, proliferation, orientation, motility, integrin expression,
cytoskeletal organization, and modulation of intracellular signaling, has
raised heightened interest in these materials for various biomedical
applications, including orthopaedic repair and regeneration. Studies have
demonstrated that nanofibrous structures can favorably modulate osteoblast,
osteoclast, and fibroblast activities toward implant and/or scaffold
materials. Nanomaterials based on silver nanoparticles have received
significant attention. Apart from their unique wound-healing ability, silver
nanoparticles also exhibit high antibacterial properties, making them
potential candidates for use in the development of infection-resistant
biomaterials.