JBJS | Foreign-Body Giant-Cell Reaction at the Donor Site After Autologous Osteochondral Transplant for Cartilaginous Lesion: A Case Report

The Journal of Bone & Joint Surgery, Volume 91, Issue 4

Case Reports | April 01, 2009

Foreign-Body Giant-Cell Reaction at the Donor Site After Autologous Osteochondral Transplant for Cartilaginous Lesion: A Case Report

Umile Giuseppe Longo, MD¹; Francesco Franceschi, MD¹; Laura Ruzzini, MD¹; Carla Rabitti, MD¹; Nicola Maffulli, MD, MS, PhD, FRCS(Orth)²; Vincenzo Denaro, MD¹

¹ Departments of Orthopaedic and Trauma Surgery (U.G.L., F.F., L.R., and V.D.) and Surgical Pathology (C.R.), Campus Biomedico University, Via Alvaro del Portillo, 200, 00155 Rome, Italy. E-mail address for U.G. Longo: g.longo@unicampus.it. E-mail address for F. Franceschi: f.franceschi@unicampus.it. E-mail address for L. Ruzzini: l.ruzzini@unicampus.it. E-mail address for C. Rabitti: c.rabitti@unicampus.it. E-mail address for V. Denaro: v.denaro@unicampus.it
² Institute of Health Sciences Education, Centre for Sports and Exercise Medicine, Mile End Hospital, 275 Bancroft Road, Mile End, London E1 4DG, United Kingdom. E-mail address: n.maffulli@qmul.ac.uk

The Journal of Bone & Joint Surgery. 2009; 91:945-949 doi:10.2106/JBJS.H.00224

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Extract

The management of chondral and osteochondral defects in weight-bearing regions of the knee is challenging, particularly in athletes. Articular cartilage has a limited capacity for regeneration, and the difficulties are magnified in the presence of full-thickness cartilage defects¹.

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Topics

cartilage ; foreign bodies ; giant cells ; tissue donors ; osteochondral allograft ; transplantation ; arthroscopy

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These activities have been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the American Academy of Orthopaedic Surgeons and The Journal of Bone and Joint Surgery, Inc. The American Academy of Orthopaedic Surgeons is accredited by the ACCME to provide continuing medical education for physicians.

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